Oxidative Status and Acute Phase Reactants in Patients with Environmental Asbestos Exposure and Mesothelioma

Table 1

The profiles of markers in different groups.

	Control	Asbestos	Mesothelioma	𝑃
TOL (mmol H2O2 equiv./L)	105.9 ± 92.5	145.1 ± 71.9^b	196.3 ± 221.1^c,d	0.001
TAC (mmol Trolox equiv./L)	0.73 ± 0.34	1.27 ± 0.16^c	0.8 ± 0.3^f	<0.001
OSI	159.3 ± 160.9	112.8 ± 48.3^c	898.6 ± 129.7^b,f	0.007
CRP (mg/dL)	2.8 ± 1.7	4.4 ± 3.1	75.6 ± 54.8^a,f	<0.001
α-1 antitrypsin (mg/dL)	146.7 ± 47.3	213.9 ± 33.9^c	262.4 ± 94.9^c,f	<0.001
Transferrin (g/L)	216.9 ± 62.3	282.8 ± 50.1^c	171.2 ± 44.5^c,f	<0.001
Ferritin (ng/mL)	112.3 ± 43.7	85.4 ± 110.6	370.7 ± 267.8^c,f	<0.001
Copper (𝜇g/mL)	0.8 ± 0.2	0.7 ± 0.3	1.2 ± 0.3^c,f	<0.001
Ceruloplasmin (mg/L)	36.6 ± 8.6	40.1 ± 9.7	42.9 ± 8.2^c,d	0.001

TOL: total oxidant level; TAC: total antioxidant capacity; OSI: oxidative stree index; CRP: C-reactive protein; ^asignificantly different from control (𝑃<0.05), ^bsignificantly different from control (𝑃<0.01), ^csignificantly different from control (𝑃<0.001), ^dsignificantly different from asbestos (𝑃<0.05), ^esignificantly different from asbestos (𝑃<0.01), and ^fsignificantly different from asbestos (𝑃<0.001).