RHBDL2 Is a Critical Membrane Protease for Anoikis Resistance in Human Malignant Epithelial Cells
Figure 2
Long-term suspension cultures triggered RHBDL2 upregulation and represent reduced apoptosis in malignant tumor cells. The expression levels of RHBDL2 in suspension-cultured breast (a) and cervical and (b) epithelial tumor cells were detected by Western blot analysis. (c) Detection of apoptotic cells under floating culture condition by using Annexin V-FITC/PI staining.