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The Scientific World Journal
Volume 2014, Article ID 918496, 5 pages
Research Article

Examination of the Ovarian Reserve after Generation of Unilateral Rudimentary Uterine Horns in Rats

1Department of Obstetrics and Gynecology, Adana Numune Education and Research Hospital, 01330 Adana, Turkey
2Department of Pharmacology, Çukurova University Medical School, Adana, Turkey
3Department of Obstetrics and Gynecology, Zeynep Kamil Education and Research Hospital, Istanbul, Turkey
4Department of Obstetrics and Gynecology, Mersin University Medical School, Mersin, Turkey

Received 18 November 2013; Accepted 30 December 2013; Published 6 February 2014

Academic Editors: R. Abir and T. Levy

Copyright © 2014 Hasan Toyganözü et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. The purpose of this experimental rat model study is to evaluate the changes in the ovarian environment after excision of the rudimentary horn. Methods. Ten female Wistar albino rats were used in this study. One cm of right uterine horn length was excised in the first operation. Two months after the first operation, all animals were sacrificed to obtain ovaries for histological examination. Mann-Whitney test and Student's -test were used for statistical analysis purposes. Statistical significance was defined as . Results. The number of primordial follicles (), primary follicles (), preantral follicles (), antral follicles (), and Graafian follicles () was decreased and the number of atretic follicles () increased in the right ovarian side. Howeve,r this difference was not found to be statistically significant. Conclusion. The results of this experimental rat model study suggest that the excision of rudimentary horn could have negative effects on ipsilateral ovarian functions.