Caenorhabditis elegans as Model System in Pharmacology and Toxicology: Effects of Flavonoids on Redox-Sensitive Signalling Pathways and Ageing

Table 2

Modulation of the mean, median, and maximum life span of C. elegans by flavonoid rich plant extracts in different studies.

Flavonoid rich extract	Concentration	Temperature	Mean life span (%)	Median life span (%)	Maximum life span (%)	References
Apple procyanidins	65 μg/mL		12	/	/	Sunagawa et al., 2011 [47]
Ginkgo biloba extract EGb 761	100 μg/mL	20°C	10	16	17	Kampkötter et al., 2007 [48]
Polyphenol-enriched cocoa powder	4 mg/mL	20°C	17	/	/	Martorell et al., 2011 [46]
Proanthocyanidins-enriched extract from blueberries	200 μg/mL	25°C	14,4 fem-1(hc17)	/	/	Wilson et al., 2006 [45]