miR-16-1 Promotes the Aberrant <i>α</i>-Synuclein Accumulation in Parkinson Disease via Targeting Heat Shock Protein 70

<table><i>α</i>-Synuclein is overexpressed in SH-SY5Y-Syn cells. (a) RT-qPCR analysis of <i>α</i>-synuclein overexpression in SH-SY5Y-Syn cell lines after serial passages, compared to <i>β</i>-actin. (b)–(d) Western blot (b) or immunofluorescence analysis ((c) and (d)) indicated <i>α</i>-synuclein overexpression in protein level in serially propagated SH-SY5Y-Syn stable cell line; results were normalized to <i>β</i>-actin. The GFP-positive cells overexpressed <i>α</i>-synuclein. Statistical significance was showed as <svg height="17.825001" id="M4" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 76.137497 17.825001" width="76.137497" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>, ns: no significance.</table>

The Scientific World Journal

fig1

Figure 1

Figure 1: miR-16-1 Promotes the Aberrant <i>α</i>-Synuclein Accumulation in Parkinson Disease via Targeting Heat Shock Protein 70 

The Scientific World Journal

miR-16-1 Promotes the Aberrant α-Synuclein Accumulation in Parkinson Disease via Targeting Heat Shock Protein 70

Figure 1