Research Article

miR-16-1 Promotes the Aberrant α-Synuclein Accumulation in Parkinson Disease via Targeting Heat Shock Protein 70

Figure 4

miR-16-1 mimics promoted α-synuclein aggregation in SH-SY5Y-Syn cells. (a) and (b) The transfection of miR-16-1 or miR con did not regulate the α-synuclein expression in mRNA level (a) or in protein level (b), revealing by RT-qPCR or western blot analysis. (c) miR-16-1 mimics transfection promoted α-synuclein aggregation in SH-SY5Y-Syn cells. All results were got from triplicate independent experiments. and ns: no significance.
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