Research Article
Characterization of Metabolites of Leonurine (SCM-198) in Rats after Oral Administration by Liquid Chromatography/Tandem Mass Spectrometry and NMR Spectrometry
Table 1
The metabolic profile of leonurine in various rat biological samples.
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N.D.: not detected. Calculated as (peak area of each compound/total peak areas of all compounds) 100. The peak areas of parent and each metabolite were obtained under MRM scan mode. cThe pooled plasma samples collected from 6 rats after oral dosing of leonurine. dThe 0–8 h bile samples collected from 6 bile duct-cannulated rats after oral dosing. eThe 0–16 h samples collected from 6 rats after oral dosing. |