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The Scientific World Journal
Volume 2014, Article ID 953181, 15 pages
http://dx.doi.org/10.1155/2014/953181
Research Article

Screening of Trace Elements in Hair of the Female Population with Different Types of Cancers in Wielkopolska Region of Poland

1Department of General Pharmacology and Pharmacoeconomics, Pomeranian Medical University in Szczecin, Zolnierska 48, 70-204 Szczecin, Poland
2Department of Pharmacology and Phytochemistry, Institute of Natural Fibers and Medicinal Plants, Wojska Polskiego 71b, 60-630 Poznan, Poland
3Department of Pharmaceutical Botany and Plant Biotechnology, Poznan University of Medical Sciences, Święty Marii Magdaleny 14, 61-861 Poznan, Poland
4Division of Perinatology and Women’s Diseases, Poznan University of Medical Sciences, Polna 33, 60-535 Poznan, Poland
5Laboratory of Molecular Biology, Poznan University of Medical Sciences, Polna 33, 60-535 Poznan, Poland

Received 24 July 2014; Revised 24 November 2014; Accepted 25 November 2014; Published 15 December 2014

Academic Editor: Jahn M. Nesland

Copyright © 2014 Bogusław Czerny et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. Cancer constitutes a major health problem worldwide. Thus, search for reliable and practical markers of the disease process remains the key issue of the diagnostic process. Objectives. The study aims at linking the trace element status of an organism, assessed by hair analysis, with the occurrence of cancer diseases. Material and Methods. Hair samples were collected from 299 patients with cancer diseases confirmed by a histopathological test and from 100 controls. Cancer patients were divided into three groups, depending on cancer type: hormone-dependent cancer, cancer of the alimentary tract, and cancer with high glycolytic activity. Mineral element analysis of hair was performed using an atomic emission spectrophotometer with inductively coupled plasma (ICP-OES) and inductively coupled plasma mass spectrometry (ICP-MS). Results. Statistically significantly lower concentrations of selenium, zinc, copper, germanium and boron, iron, and magnesium were observed in the three groups of cancer patients. Disturbance in the axis glucose-insulin and changes in concentrations of heavy metals and toxic elements were also noted. Conclusions. It seems safe to conclude that our results confirmed usefulness of hair element analysis in screening tests for the assessment of the biomarker of various cancer diseases in a female population.