Identification of Family Specific Fingerprints in β-Lactamase Families

Table 1

List of fingerprints in different families of β-lactamase. (^@fingerprint is extracted from more than one sequence with evidence at protein existence level; ^#only one sequence has evidence at protein existence level, and hence proteins whose existence is not experimentally proven were also selected; *only sequences without evidence of protein existence were present in the family, and hence fingerprint is based on nonexperimentally existence proteins; ^Ωonly one sequence is present in the family with evidence of protein existence; ^¥only one sequence is present in the family whose existence is not proven at protein level).

Class	Sr. number	Family	Sequence	Fingerprint
				Width	𝐸-value	Sequence logo	Regular expression
A	1	AER^¥	1	NA	NA	NA	NA
	2	AST^#	4	10	2.3𝑒−013		[EQ]R[FM]P[MF][ACL]STFK
	3	BEL*	3	10	1.0𝑒−11		WVTGDKTGSC
	4	BES^¥	1	NA	NA	NA	NA
	5	BLAF^#	4	10	6.5𝑒−017		F[AP][MI][CA]S[TM]FK[TAG][YI]
	6	BLAZ*	5	10	5.7𝑒−021		SRNDVAFVYP
	7	BPS*	5	10	3.0𝑒−038		FPFCSTSKMM
	8	BRO*	15	10	3.3𝑒−145		MQRRHFLQKT
	9	Carb^#	16	10	6.2𝑒−113		CFATMTTSDN
	10	CEPA*	6	10	1.4𝑒−043		EFCYQNWTTP
	11	CFXA*	5	10	4.6𝑒−028		FQIAYTEEEM
	12	CKO*	3	10	1.1𝑒−016		MWQRMKWGLC
	13	ClbA*	6	10	5.9𝑒−038		LRYNDHVHFP
	14	CME*	3	10	2.3𝑒−014		WSPLREKYPD
	15	CSP^¥	1	NA	NA	NA	NA
	16	CTXM^@	6	10	3.6𝑒−039		NYNPIAEKHV
	17	CumA^γ	1	NA	NA	NA	NA
	18	DES^¥	1	NA	NA	NA	NA
	19	FAR*	2	3	2.2𝑒−001		FG[HM]
	20	ERP^¥	1	NA	NA	NA	NA
	21	FONA*	6	10	4.5𝑒−045		YRGDERFPMC
	22	FEC-1^¥	1	NA	NA	NA	NA
	23	GES^@	5	10	1.6𝑒−020		HRMAQRFAMC
	24	HUGA^¥	1	NA	NA	NA	NA
	25	HERA*	3	10	3.9𝑒−011		QWMRDDKVGD
	26	IRT^¥	1	NA	NA	NA	NA
	27	KLUA*	8	10	7.5𝑒−060		YRADERFAMC
	28	KLUC*	3	10	1.3𝑒−013		YRGDERFAMC
	29	KLUG^¥	1	NA	NA	NA	NA
	30	KLUY*	5	10	9.5𝑒−034		YRGDERFPMC
	31	KPC^@	2	9	1.6𝑒−004		PNKDDKHSE
	32	LAP*	4	10	1.2𝑒−020		HRREERFPMM
	33	Len^@	5	10	1.4𝑒−116		ERFPMVSTFK
	34	LUT*	6	10	1.0𝑒−037		TYSPVTEKHV
	35	MAL*	2	10	1.1𝑒−007		MWQRMKWGLC
	36	NMC^#	2	10	2.6𝑒−005		EHEKETYQTW
	37	OHIO^¥	1	NA	NA	NA	NA
	38	OKP*	23	10	1.9𝑒−217		VDYSPVSEKH
	39	ORN*	6	10	5.6𝑒−043		ERFPMMSTFK
	40	OXY^@	2	10	2.3𝑒−006		YRGDERFAMC
	41	PENA^#	15	10	2.3𝑒−119		ERFPFCST[SF]K
	42	PER^#	14	10	4.2𝑒−107		NPFEKFPMQS
	43	PLA*	4	10	9.4𝑒−024		ERFPMMSTFK
	44	PSE*	37	10	9.1𝑒−351		WDYNGNQRFP
	45	RAHN*	2	10	6.3𝑒−005		YRADERFAMC
	46	RTG*	2	9	3.7𝑒−005		MWPPNRKPI
	47	ROB*	11	10	3.9𝑒−086		VYVWDTETGH
	48	SCO*	5	10	3.2𝑒−025		W[FQ][HY]RA[DN][DE]RFP
	49	SED^Ω	1	NA	NA	NA	NA
	50	SFC^Ω	1	NA	NA	NA	NA
	51	SFO*	2	10	1.1𝑒−007		YRGDERFPMC
	52	SHV^@	8	10	2.1𝑒−043		FPMMSTFKVV
	53	SME^#	4	10	9.9𝑒−020		YRSDERFPLC
	54	TEM^@	4	10	2.1𝑒−031		HYSQNDLV[EK]Y
	55	TER*	2	10	9.4−006		FPMMSTFKVP
	56	TLA*	2	10	1.1𝑒−004		E[CM]H[EK][AS]WNVQY
	57	TOHO^#	4	10	4.5𝑒−018		YR[AEG][DN]ERF[AP]MC
	58	VHH^¥	1	NA	NA	NA	NA
	59	VHW^¥	1	NA	NA	NA	NA
	60	VEB*	20	10	1.3𝑒−193		DFHFPMQSVM
	61	ACI^¥	1	NA	NA	NA	NA
B1	1	Blab*	12	10	1.3𝑒−091		NIATHSHDDR
	2	CcrA^Ω	1	NA	NA	NA	NA
	3	CGB^¥	1	NA	NA	NA	NA
	4	DIM*	2	10	2.3𝑒−004		HIDQWSRSAQ
	5	EBR^¥	1	NA	NA	NA	NA
	6	GIM*	7	10	8.4𝑒−051		WATDRGYQVM
	7	IMP^@	2	10	1.8𝑒−002		RKILFGGCFI
	8	IND^#	19	10	1.6𝑒−160		FATHSHDDRA
	9	JOHN^¥	1	NA	NA	NA	NA
	10	KHM^¥	1	NA	NA	NA	NA
	11	NDM^@	2	10	4.6𝑒−005		ILNWIKQEIN
	12	SFB^¥	1	NA	NA	NA	NA
	13	SIM*	3	10	2.6𝑒−0111		MRTLLILCLF
	14	SLB^¥	1	NA	NA	NA	NA
	15	SPM^Ω	1	NA	NA	NA	NA
	16	TMB*	2	10	1.2𝑒−006		DQWPQSARNT
	17	TUS^¥	1	NA	NA	NA	NA
	18	MUS^¥	1	NA	NA	NA	NA
	19	VIM^@	4	10	1.4𝑒−015		IDTAWGAKNT
B2	1	CphA^#	12	10	1.2𝑒−079		QTRDLMKSDW
	2	Sfh^Ω	1	NA	NA	NA	NA
	3	ImiS^¥	1	NA	NA	NA	NA
B3	1	AIM^Ω	1	NA	NA	NA	NA
	2	AMO^¥	1	NA	NA	NA	NA
	3	L1^#	31	10	4.7𝑒−267		HFMPGHTPGS
	4	BJP^¥	1	NA	NA	NA	NA
	5	CAU^¥	1	NA	NA	NA	NA
	6	CRB^¥	1	NA	NA	NA	NA
	7	FEZ^Ω	1	NA	NA	NA	NA
	8	GOB*	5	10	1.1𝑒−032		HHPGHTKGSC
	9	LRA*	12	10	4.2𝑒−027		YYV[GF][TN]Y[DG]L[AG][CS]
	10	Mlb1b^Ω	1	NA	NA	NA	NA
	11	POM^¥	1	NA	NA	NA	NA
	12	SMB^Ω	1	NA	NA	NA	NA
	13	Thin-B^¥	1	NA	NA	NA	NA
	1	ACT^Ω	1	NA	NA	NA	NA
	2	ACC*	9	10	7.6𝑒−063		PELRGSSFDH
	3	BIL^¥	1	NA	NA	NA	NA
	4	CFE^¥	1	NA	NA	NA	NA
	5	CMY^#	86	10	3.8𝑒−833		RYWRIGDMYQ
	6	DHA*	11	10	1.4𝑒−078		WEMYDWPQQK
C	7	EBC^¥	1	NA	NA	NA	NA
	8	FOX*	11	10	3.7𝑒−081		DKM[RQ]TYYR[SH]W
	9	LAT*	3	10	8.5𝑒−013		HFYQNW[QL]PQW
	10	MIR*	6	10	1.0𝑒−039		RFYQNWQPQW
	11	MOX*	6	10	3.8𝑒−031		EKMQAYYRQW
	12	SRT*	2	10	3.5𝑒−055		KWFPNDDRVE
	13	SST^¥	1	NA	NA	NA	NA
D	1	OXA^@	6	10	4.1𝑒−017		Y[LS]PASTFKIP
	2	LCR*	5	10	2.3𝑒−021		F[PK][NAV]SCV[PW][AC]YQ