Protective Action of Antioxidants on Hepatic Damage Induced by Griseofulvin

Figure 3

Effect of antioxidants on liver antioxidant defense system. (a) GRed, mean control value: 43.52±7.40 nmol/mg protein (n-6); (b) SOD, mean control value: 83.90±8.66 nmol/mg protein (n-6); and (c) GST, mean control value: 22.77±1.20 μnmol/mg protein (n-6). ^∗∗𝑃<0.01: Significant difference between the group treated with Gris alone or Gris plus antioxidant and the control group. ⁺𝑃<0.05 and ⁺⁺𝑃<0.01: significant difference between the group treated with Gris plus antioxidant and the group that only received Gris. ^#𝑃<0.05 and ^##𝑃<0.01: significant difference between the group treated with antioxidants andthe control group. ^†𝑃<0.05 and ^††𝑃<0.01: significant difference between the group treated with Gris plus antioxidant and group only treated with antioxidant. Experimental details are described in legend to Figure 1 and in Section 2.

(a)

(b)

(c)