Intravitreal Steroids for the Treatment of Retinal Diseases
Figure 1
Distribution of change in visual acuity (ETDRS letters) between baseline and month 12 (unless otherwise specified) for large, controlled, and randomized clinical trials investigating steroids in diabetic macular edema and macular edema secondary to retinal vein occlusion. GENEVA (6 months): 700 µg dexamethasone implant. SCORE: 4 mg intravitreal triamcinolone acetonide. DRCR prot B: 4 mg intravitreal triamcinolone acetonide. DRCR prot I: 4 mg intravitreal triamcinolone acetonide plus laser photocoagulation. FAME (24 months): 0.2 μg/day fluocinolone implant. GENEVA and FAME publications did not disclose distribution of change other than the percentage of patients showing ETDRS letters gain.
