Nanoparticle Properties and Synthesis Effects on Surface-Enhanced Raman Scattering Enhancement Factor: An Introduction

Table 1

A list of molecules used for SERRS enhancement for excitation wavelengths () from 514–785 nm and their associated absorption maximums ().

Raman reporter	(nm)	(nm)	Reference
Carboxyfluorescein (FAM)	494	514.5	[85]
Rhodamine 6 G (R6G)	524	514.5, 532	[85–88]
TRITC-DHPE	540	514.5	[89]
Carboxy-X-rhodamine (ROX)	585	514.5, 632.8	[85]
BIODIPY TR-X	588	632.8	[85]
Crystal violet (CV)	590	514.5, 647.1	[86, 90]
Malachite green (MG)	618	632.8	[91]
Malachite green isothiocyanate (MGITC)	625	632.8	[91]
Methylene blue	570–760^∤	785	[92, 93]
Cy5.5	683	632.8	[85]
3,3′-diethylthiatricarbocyanine iodide (DTTC)	765	785	[94]

Methylene blue (MB) has various different maximum absorption points due to the formation of molecular aggregates and protonation states. The formation of dimer and trimer aggregates and MB protonation causes a shift in the maximum absorption. As a result, the maximum absorption is directly related to the state of the MB molecule during measurement [93].