Research Article

Effects of 5-Amyno-4-(1,3-benzothyazol-2-yn)-1-(3-methoxyphenyl)-1,2-dihydro-3H-pyrrol-3-one Intake on Digestive System in a Rat Model of Colon Cancer

Table 6

Blood serum parameters for rats treated by D1 and 5FU under DMH-induced carcinogenesis. Mean ± SEM, .

ALT, nmol pyruvate/mg protein per minAST, nmol pyruvate/mg protein per minALP, nmol 4-nitrophenol/mg protein per minLDH, nmol pyruvate/mg protein per min

Control0.43 ± 0.040.57 ± 0.047.3 ± 0.2714.6 ± 2.7
0.32 ± 0.040.57 ± 0.057.57 ± 0.2213.5 ± 2.16
0.34 ± 0.030.59 ± 0.077.3 ± 0.2714.04 ± 2.7
5FU0.39 ± 0.030.44 ± 0.077.01 ± 0.2513.9 ± 2.9
DMH0.52 ± 0.030.43 ± 0.0410.38 ± 0.3216.2 ± 3.24
DMH + 0.52 ± 0.020.54 ± 0.047.35 ± 0.2714.31 ± 2.7
DMH + 0.52 ± 0.040.53 ± 0.057.14 ± 0.3213.5 ± 2.43
DMH + 5FU0.53 ± 0.040.53 ± 0.047.42 ± 0.3115.3 ± 2.57

values indicated in comparison with control; compared to DMH group.