Mechanism of Gene Amplification via Yeast Autonomously Replicating Sequences

<table class="table-group" id="tab9"><tr><td><table class="table"><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr class="thead"><td align="left">RE sequences </td><td align="center">CEO ARS/FRA sequences with RE </td></tr><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr><td align="left">CGGAGGGGCCCTAGAGGGCCCTAGAG<br/>GGCCCCCCAAAAACCCCCAAAAACCC<br/>CCC </td><td align="center">ARS1127 </td></tr><tr><td align="center" colspan="2"><hr/></td></tr><tr><td align="left">TCTCTAAAAAATATATAAAAA </td><td align="center">                    — </td></tr><tr><td align="center" colspan="2"><hr/></td></tr><tr><td align="left">AAAAAAAAAAAAAAAAAAAA </td><td align="center">ARS606, ARS1305, ARS105, ARS112, ARS431, ARS520, ARS606, ARS733, ARS1305, ARS1330, ARS112, FRAII </td></tr><tr><td align="center" colspan="2"><hr/></td></tr><tr><td align="left">CATGTCACCGACGCATCACCG </td><td align="center">                   — </td></tr><tr><td align="center" colspan="2"><hr/></td></tr><tr><td align="left">ATACACAGAAAATAGAAATGTCTTAA<br/>ATTTTTATATTTTTCACACTTTAAAGT </td><td align="center">ARS215, ARS452, ARS440, ARS602, ARS110, ARS733, ARS920, ARS1021, ARS1127, ARS1211, ARS220, ARS215</td></tr><tr><td align="center" colspan="2"><hr/></td></tr><tr><td align="left">AGGGCCCTAGAGGGGCCCTAG</td><td align="center">                   —</td></tr><tr class="table-tr"><td colspan="2"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Presence of RE sequences in APS of <i>S. cerevisiae</i> and FRA11A.

The Scientific World Journal

tab9

Table 9

Table 9: Mechanism of Gene Amplification via Yeast Autonomously Replicating Sequences 