Research Article

Efficacy and Safety of Miltefosine in Treatment of Post-Kala-Azar Dermal Leishmaniasis

Table 1

Hematological and biochemical characteristics of patients at baseline and at 2, 4, and 12 weeks.

0 week 2 weeks 4 weeks 12 weeks value
0 versus 20 versus 40 versus 12

WBC(/L)
Median (IQR)
8500.00
(6950.00–10600.00)
9200.00
(7250.00–10300.00)
9300.00
(7850.00–11000.00)
8100.00
(6200.00–10900.00)
0.0290.1380.808
Hemoglobin (gm/dL)
Median (IQR)
11.600
(10.100–13.850)
11.400
(10.500–13.000)
11.400
(9.900–12.950)
11.000
(8.650–12.950)
0.5000.7150.070
Platelets (/L)
Median (IQR)
252000
(216000–309000)
278000
(224000–354000)
302000
(251500–374000)
278000
(169000–338000)
0.0130.0090.955
BUN (mg/dL)
Median (IQR)
9.40
(7.17–12.08)
8.93
(6.28–10.68)
10.30
(8.58–11.58)
9.635 (7.050–9.635)0.3060.3300.961
SGOT (IU)
Median (IQR)
27.00
(19.50–32.50)
26.00
(20.50–30.50)
24.00
(10.50–30.50)
27.00 (16.50–36.00)0.6170.2060.851
SGPT (IU)
Median (IQR)
31.00
(23.00–37.00)
28.00
(21.00–39.00)
29.00
(19.50–48.50)
23.00 (14.50–34.00)0.6310.4320.033
Serum creatinine (mg/dL)
Median (IQR)
0.6800
(0.5800–0.8800)
0.7500
(0.6600–0.9250)
0.780
(0.650–1.045)
0.7400
(0.5850–1.0850)
0.0060.0040.194

IQR: interquartile range.
BUN: blood urea nitrogen.
SGOT: serum glutamic oxaloacetic transaminase.
SGPT: serum glutamic pyruvic transaminase.