Research Article
Efficacy and Safety of Miltefosine in Treatment of Post-Kala-Azar Dermal Leishmaniasis
Table 1
Hematological and biochemical characteristics of patients at baseline and at 2, 4, and 12 weeks.
| |
0 week |
2 weeks |
4 weeks |
12 weeks | value | 0 versus 2 | 0 versus 4 | 0 versus 12 |
| WBC(/L) Median (IQR) | 8500.00 (6950.00–10600.00) | 9200.00 (7250.00–10300.00) | 9300.00 (7850.00–11000.00) | 8100.00 (6200.00–10900.00) | 0.029 | 0.138 | 0.808 | Hemoglobin (gm/dL) Median (IQR) | 11.600 (10.100–13.850) | 11.400 (10.500–13.000) | 11.400 (9.900–12.950) | 11.000 (8.650–12.950) | 0.500 | 0.715 | 0.070 | Platelets (/L) Median (IQR) | 252000 (216000–309000) | 278000 (224000–354000) | 302000 (251500–374000) | 278000 (169000–338000) | 0.013 | 0.009 | 0.955 | BUN (mg/dL) Median (IQR) | 9.40 (7.17–12.08) | 8.93 (6.28–10.68) | 10.30 (8.58–11.58) | 9.635 (7.050–9.635) | 0.306 | 0.330 | 0.961 | SGOT (IU) Median (IQR) | 27.00 (19.50–32.50) | 26.00 (20.50–30.50) | 24.00 (10.50–30.50) | 27.00 (16.50–36.00) | 0.617 | 0.206 | 0.851 | SGPT (IU) Median (IQR) | 31.00 (23.00–37.00) | 28.00 (21.00–39.00) | 29.00 (19.50–48.50) | 23.00 (14.50–34.00) | 0.631 | 0.432 | 0.033 | Serum creatinine (mg/dL) Median (IQR) | 0.6800 (0.5800–0.8800) | 0.7500 (0.6600–0.9250) | 0.780 (0.650–1.045) | 0.7400 (0.5850–1.0850) | 0.006 | 0.004 | 0.194 |
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IQR: interquartile range. BUN: blood urea nitrogen. SGOT: serum glutamic oxaloacetic transaminase. SGPT: serum glutamic pyruvic transaminase.
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