Research Article
The Effects of Tempol on Cyclophosphamide-Induced Oxidative Stress in Rat Micturition Reflexes
Figure 8
Representative cystometrogram recordings using continuous intravesical infusion of saline in conscious rats with an open outlet from a CYP-treated (48 hr) rat with vehicle ((a1)–(a3)) and a CYP-treated (48 hr) rat with Tempol (1 mM; (b1)–(b3)). ((a), (b)) Bladder function in a CYP-treated (48 hr) rat without Tempol (vehicle only; (a1)–(a3)) and in a CYP-treated (48 hr) rat with Tempol (1 mM in the drinking water; (b1)–(b3)) during continuous intravesical infusion of saline. Bladder function recordings in (a) and (b) are from different rats. Infused volume (IF, μL; (a1), (b1)), bladder pressure (BP, cm H2O; (a2), (b2)), and void volume (VV, mL; (a3), (b3)) with vehicle ((a1)–(a3)) and with Tempol treatment ((b1)–(b3)) are shown.
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