Evidence for Negative Effects of Elevated Intra-Abdominal Pressure on Pulmonary Mechanics and Oxidative Stress
Table 2
Pre- and perioperative levels of respiratory parameters and measurements of AKG in patients who underwent laparoscopic cholecystectomy and abdominal wall hernia.
Laparoscopy group
Abdominal wall hernia group
Baseline
30th minute
End of surgery
Baseline
30th minute
End of surgery
PIP
20 (16–32)
22 (19–33
20 (17–32)c
23 (20–27)
23 (18–28)
23 (20–28)
PLT
20 (11–33)
21 (10–36)
20 (12–33)
19 (15–27)
20 (14–27)
20 (15–25)
Cdyn
28.50 (22.72–38.55)
21.53 (17.30–29.41
28.50 (22.70–38.55)c
26.31 (20.50–35.61)
26.30 (20.53–35.62)
26.31 (20.52–35.60)
pO2
202 (122–268)
125 (53–226
162 (110–250
185 (102–279)
189 (120–270)
185 (123–340)
pCO2
38 (31–52)
45 (34–59
44 (27–60
41 (32–52)
39 (32–53)
40 (19–52)
pH
7.39 (7.31–7.49)
7.34 (7.24–7.50
7.35 (7.26–7.48
7.39 (7.33–7.44)
7.40 (7.29–7.46)
7.38 (7.30–7.55)
ETCO2
31 (30–33)
35 (34–36
31 (30–32)c
31 (29–33)
32 (28–34)
31 (29–33)
Data are expressed as median (min–max). Statistically significant differences ( < 0.05) were noted as follows: a; baseline versus 30th minute, b: baseline versus end of surgery, c; 30th versus end of surgery. ; Laparoscopy group versus abdominal wall hernia group. PIP: peak in respiratory pressure, PLT: plateau pressure, Cdyn: dynamic lung compliance, ETCO2: end-tidal CO2.
