Radiotracers Used for the Scintigraphic Detection of Infection and Inflammation

Table 6

Status of monoclonal antibodies in 2009 [147].

mAb species origin	Number of mAb products (fraction)
	Of total	In market^a	Withdrawn; from market	In preclinical or; clinical trials	Radiolabeled mAbs^b
					In	Withdrawn
Murine	36/242	7/36	8/36	21/36	3/7	7/8
Chimeric^c	24/242	11/24	0/24	13/24	0/11	0/0
Humanized^d	127/242	12/127	1/127	114/127	0/12	1/1
Human	55/242	2/55	2/55	51/55	0/2	1/2

Achieved market authorization and commercially available; ^bdiagnostic and therapy radioisotopes; ^cstructure contains one species other than human; ^dstructure contains variable chains not human.