Review Article
Association between Polymorphism of Interleukin-1beta and Interleukin-1 Receptor Antagonist Gene and Asthma Risk: A Meta-Analysis
Table 2
Main data of all studies included in the meta-analysis for the polymorphism in IL-1RA gene.
| Reference, year | Ethnicity | Source of control | Mean of age (years) | Cases/control | Cases | Control | (country) | GG | GA | AA | GG | GA | AA |
| Birbian et al. 2013 [37] | Asian (India) | PB | 38.1 | 815/825 | 593 | 214 | 8 | 653 | 162 | 10 | Hang et al. 2003 [35] | Asian (Taiwan) | HB | 27.4 | 115/47 | 101 | 12 | 2 | 39 | 8 | 0 | Lim et al. 2011 [28] | Asian (Singapore) | HB | 63.5 | 294/710 | 251 | 40 | 3 | 621 | 89 | 0 | Mahdaviani et al. 2009 [30] | Caucasian (Iran) | HB | 17.9 | 37/140 | 35 | 2 | 0 | 80 | 56 | 4 | Pattaro et al. 2006 [34] | Caucasian (Germany) | PB | 23.6 | 604/905 | 356 | 207 | 41 | 538 | 315 | 52 | Pillay et al. 2000 [36] | Caucasian (African) | PB | 26 | 149/209 | 119 | 26 | 4 | 165 | 41 | 3 | Ramadas et al. 2007 [33] | Caucasian (USA) | PB | 10 | 419/3057 | 242 | 142 | 35 | 1721 | 1150 | 186 | Rezaei et al. 2009 [29] | Caucasian (Iran) | PB | 6.5 | 29/140 | 15 | 12 | 2 | 80 | 56 | 4 | Settin et al. 2008 [32] | Caucasian (Egypt) | HB | 7.5 | 70/98 | 63 | 6 | 1 | 57 | 41 | 0 | Zeyrek et al. 2008 [31] | Caucasian (Turkey) | PB | 9.4 | 268/228 | 54 | 168 | 46 | 66 | 136 | 26 |
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HB: hospital-based case-control; PB: population-based case-control.
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