Review Article

Association between Polymorphism of Interleukin-1beta and Interleukin-1 Receptor Antagonist Gene and Asthma Risk: A Meta-Analysis

Table 2

Main data of all studies included in the meta-analysis for the polymorphism in IL-1RA gene.

Reference, yearEthnicitySource of controlMean of age (years)Cases/controlCasesControl
(country)GGGAAAGGGAAA

Birbian et al. 2013 [37]Asian (India)PB38.1815/825593214865316210
Hang et al. 2003 [35]Asian (Taiwan)HB27.4115/471011223980
Lim et al. 2011 [28]Asian (Singapore)HB63.5294/710251403621890
Mahdaviani et al. 2009 [30]Caucasian (Iran)HB17.937/140352080564
Pattaro et al. 2006 [34]Caucasian (Germany)PB23.6604/9053562074153831552
Pillay et al. 2000 [36]Caucasian (African)PB26149/209119264165413
Ramadas et al. 2007 [33]Caucasian (USA)PB10419/30572421423517211150186
Rezaei et al. 2009 [29]Caucasian (Iran)PB6.529/1401512280564
Settin et al. 2008 [32]Caucasian (Egypt)HB7.570/98636157410
Zeyrek et al. 2008 [31]Caucasian (Turkey)PB9.4268/22854168466613626

HB: hospital-based case-control; PB: population-based case-control.