Discovery of Specific Inhibitors for Intestinal E. coli  β-Glucuronidase through In Silico Virtual Screening

Figure 3

Binding model of compound 7145. Predicted binding mode of compound 7145 in the active site of eG from the docking study. Compound 7145 (yellow) and some amino acid residues (cyan) interacting with the inhibitor are shown as stick structures. The red dashed lines indicate hydrogen-bonding interactions. The residue L361 (purple) in the bacterial loop makes hydrophobic contact with compound 7145.