Antimycobacterial and Nitric Oxide Production Inhibitory Activities of Ocotea notata from Brazilian Restinga

Figure 2

(a) Inhibitory effect of Mycobacterium bovis BCG growth by extracts and fractions of leaves of Ocotea notata tested at four different concentrations, 0.8, 4, 20, and 100 μg/mL. The percentage of inhibition was compared with the positive control (rifampicin): .: and negative control (mycobacteria without treatment) .: . (b) Cytotoxicity of the extracts and fractions of leaves of Ocotea notata tested at four different concentrations 0.8, 4, 20, and 100 μg/mL in murine macrophages RAW 264.7. The percentages were compared to positive control, macrophages treated with Triton 1%: .: 0.132, and negative control, macrophages without treatment .: 0.749. ^∗, ^∗∗, and ^∗∗∗, significance obtained by ANOVA and posttest Tukey (), when compared to the negative control (a) and positive control (b).

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