Antimycobacterial and Nitric Oxide Production Inhibitory Activities of Ocotea notata from Brazilian Restinga

Figure 5

(a) Inhibitory effect of Mycobacterium bovis BCG growth by Acet22 (isoquercitrin) tested at four different concentrations, 0.8, 4, 20, and 100 μg/mL. The percentage of inhibition was compared with the positive control (rifampicin), .: , and negative control (medium + mycobacteria), .: . (b) Cytotoxicity of Acet22 (isoquercitrin) tested at four different concentrations 0.8, 4, 20, and 100 μg/mL in murine macrophages RAW 264. The percentages were compared to positive control, macrophages treated with Triton 1%: .: 0.132, and negative control, macrophages without treatment .: 0.749. ^∗, ^∗∗, and ^∗∗∗, significance obtained by ANOVA and posttest Tukey (), when compared to the negative control (a) and positive control (b).

(a)

(b)