Elevation of Glucose 6-Phosphate Dehydrogenase Activity Induced by Amplified Insulin Response in Low Glutathione Levels in Rat Liver

<div>Effect of BSO on glutathione concentration and G6PD activity of isolated cultured hepatocytes. Isolated rat hepatocytes were incubated for 48 h in WE medium containing 10<sup>−6 </sup>M dexamethasone, 0.1 <i>μ</i>g/mL aprotinin, 30 <i>μ</i>g/mL kanamycin, and 10<sup>−7</sup> M insulin in the presence of 0–0.5 mM BSO. Glutathione level (closed circle) and G6PD activity (open circle) were determined at each BSO concentration.</div>

The Scientific World Journal

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Figure 4

Figure 4: Elevation of Glucose 6-Phosphate Dehydrogenase Activity Induced by Amplified Insulin Response in Low Glutathione Levels in Rat Liver 