Assessment of Cytotoxic Activity of Rosemary (Rosmarinus officinalis L.), Turmeric (Curcuma longa L.), and Ginger (Zingiber officinale R.) Essential Oils in Cervical Cancer Cells (HeLa)
Morphological changes in HeLa cells treated with R. officinalis (REO), C. longa (CEO), and Z. officinale (GEO) essential oils and dyed with Giemsa. (A) Positive control: cell population treated with DMSO; (B) negative control: cell population without influence of treatment; (C–E) cells treated with 31.12; 249; and 1992 μg/mL of REO; (F–H) cells treated with 32.81; 262; and 2100 μg/mL of CEO; (I–K) cells treated with 30.12; 241; and 1928 μg/mL of GEO. Cell density 1 × 106 cells/mL. Images taken at 40x magnification. ( cell membrane protrusions (“blebs”); ▸ chromatin condensation; cell content leakage and formation of apoptotic bodies.)
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