In Vitro Antifungal Activity of Hexahydropyrimidine Derivatives against the Causative Agents of Dermatomycosis

Figure 1

Electron micrographs of T. mentagrophytes ATCC 9538 exposed or not to the reference drugs and hexahydropyrimidine derivative of interest. (a) T. mentagrophytes ATCC 9538 not subjected to pharmacological treatment; (b) T. mentagrophytes ATCC 9538 subjected to treatment with terbinafine; (c) T. mentagrophytes ATCC 9538 subjected to treatment with ketoconazole; (d) T. mentagrophytes ATCC 9538 subjected to treatment with HHP1; (e) T. mentagrophytes ATCC 9538 subjected to treatment with HHP3; (f) T. mentagrophytes ATCC 9538 subjected to treatment with HHP4. Arrows indicate the appearance of wrinkled (I) and crushed (II) hyphae.

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