Research Article
QT and QTc in Male Patients with Psychotic Disorders Treated with Atypical Neuroleptics
Table 1
Characteristics of the sample
.
| | | Overall sample
| Clozapine
| Olanzapine
| Risperidone
| Aripiprazole
| Quetiapine
| Paliperidone
|
| | Age (mean ± SD) | 43.0 ± 15.0 | 39.5 ± 12.8 | 42.3 ± 14.1 | 37.3 ± 12.6 | 38.3 ± 11.6 | 47.3 ± 16.3 | 41.3 ± 16.9 | | Age at onset | 24.0 ± 14.1 | 22.7 ± 13.0 | 25.7 ± 14.7 | 22.1 ± 9.4 | 18.6 ± 4.0 | 24.4 ± 16.2 | 31.2 ± 17.3 | | Illness duration (ys) | 18.7 ± 13.3 | 16.7 ± 10.3 | 16.5 ± 11.7 | 14.9 ± 10.6 | 19.7 ± 11.3 | 22.4 ± 16.2 | 13.5 ± 9.4 | | Body mass index | 26.5 ± 4.2 | 26.3 ± 4.8 (18–37) | 25.6 ± 3.3 (22–33) | 25.0 ± 2.1 (21–29) | 29.5 ± 5.2 (23–40) | 26.2 ± 4.2 (19–41) | 26.7 ± 2.0 (25–28) | | Potassium | 4.0 ± 0.4 | 3.9 ± 0.3 (3.2–4.5) | 3.9 ± 0.3 (3.0–4.5) | 4.1 ± 0.4 (3.6–5.1) | 4.0 ± 0.4 (3.3–5.3) | 3.9 ± 0.4 (3.3–5.2) | 4.1 ± 0.5 (3.3–5.0) | | Sodium | 140.9 ± 2.4 | 140.5 ± 3.5 (133–145) | 140.6 ± 2.9 (135–145) | 140.6 ± 2.2 (137–145) | 141.1 ± 1.1 (139–143) | 140.7 ± 2.4 (131–145) | 142.5 ± 1.5 (140–145) | | Calcium | 9.3 ± 0.3 | 9.4 ± 0.3 (9.0–10.0) | 9.1 ± 0.4 (8.1–9.8) | 9.4 ± 0.2 (9.1–9.7) | 9.5 ± 0.3 (8.9–10.1) | 9.3 ± 0.3 (8.1–10.2) | 9.3 ± 0.2 (8.8–9.3) | | Glycemia | 84.3 ± 16.3 | 86.2 ± 18.5 (55–121) | 83.1 ± 15.3 (60–119) | 77.5 ± 7.1 (63–87) | 86.8 ± 17.1 (67–134) | 86.9 ± 19.9 (64–165) | 78.6 ± 9.1 (64–93) | | Total cholesterol | 172.1 ± 40.1 | 150.5 ± 30.8 (102–223) | 178.2 ± 52.4 (123–290) | 169.9 ± 28.9 (119–242) | 206.8 ± 52.3 (124–295) | 162.5 ± 33.2 (88–229) | 182.8 ± 29.6 (150–242) | | Triglycerides | 146.0 ± 79.0 | 155.7 ± 57.4 (93–259) | 141.0 ± 65.5 (47–225) | 106.1 ± 22.3 (67–138) | 171.7 ± 97.8 (37–339) | 150.1 ± 94.5 (56–492) | 135.7 ± 57.1 (63–248) | | HDL | 41.9 ± 13.7 | 33.2 ± 11.6 (18–53) | 43.4 ± 15.1 (27–81) | 40.9 ± 7.7 (30–55) | 45.6 ± 18.4 (29–93) | 42.8 ± 13.6 (22–84) | 42.1 ± 12.5 (18–59) | | LDL | 107.3 ± 36.6 | 95.4 ± 29.7 (49–151) | 106.2 ± 51.1 (50–215) | 108.3 ± 24.1 (63–164) | 132.1 ± 49.3 (56–235) | 97.0 ± 30.9 (38–155) | 119.7 ± 24.7 (91–153) | | CK | 313.1 ± 1160.9 | 329.6 ± 651.9 (22–2375) | 227.5 ± 298.5 (44–942) | 201.1 ± 194.4 (60–673) | 85.8 ± 57.2 (32–202) | 448.9 ± 1813.4 (24–9692) | 237.6 ± 160.5 (35–467) | | TSH | 1.4 ± 1.0 | 1.4 ± 1.3 (0.2–4.1) | 1.2 ± 0.9 (0.2–3.2) | 1.5 ± 0.7 (0.4–2.4) | 1.2 ± 0.6 (0.2–2.4) | 1.4 ± 1.1 (0.1–4.9) | 1.2 ± 0.8 (0.4–3.0) |
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