| Medicinal use | Parts of the plant used | Country | References |
| Antidote | Root and stem bark | Cameroon | [27] |
| Anthrax | Leaves | Rwanda | [44] |
| Aphrodisiac | Leaves and stem bark | DRC | [45] |
| Conjunctivitis and eye problems | Bark, leaves, leaf sap, roots and stem bark | Cameroon, Nigeria, South Africa and Swaziland | [26–29, 32, 33, 46–49] |
| Diabetes | Leaves and stem bark | DRC and Nigeria | [29, 45] |
| Epilepsy | Stem bark | Swaziland | [46, 47] |
| Gastro-intestinal problems | | | |
| Diarrhoea, dysentery and stomach ache | Bark, leaves and roots | DRC, Madagascar, Mozambique, South Africa and Tanzania | [26, 30–36] |
| Haemorrhoids | Leaves, roots and stem bark | Nigeria and South Africa | [29, 32] |
| Headache | Bark and stem bark | Cameroon and South Africa | [26, 33, 50] |
| Hiccup | Leaves and stem bark | DRC | [45] |
| Hypertension | Leaves | Togo | [37] |
| Love charm | Bark | South Africa | [17, 25, 26] |
| Memory loss and neurodegenerative disorders | Leaves and roots | Nigeria and South Africa | [32, 51] |
| Purgative | Bark, leaves and roots | Cameroon and South Africa | [26, 28, 31–33] |
| Respiratory problems | | | |
| Bronchitis, cough, respiratory problems and sinusitis | Bark, leaves and stem bark | Cameroon, Mozambique, Nigeria and South Africa | [25–29] |
| Reproductive problems in women | | | |
| Sterility and uterine problems | Bark, leaves and roots | Cameroon and Swaziland | [47, 49, 52] |
| Sexually transmitted infections |
| Gonorrhoea, Sexually transmitted diseases and syphilis | Bark, leaves, roots and stem bark | Cameroon, DRC, Guinea, Nigeria, Rwanda, Swaziland and Uganda | [29, 45–47, 49, 53–55] |
| Gonorrhoea | Stem bark mixed with Citrus aurantiifolia (Christm.) Swingle fruits | Sierra Leone | [41] |
| Syphilis | Leaves mixed with Trichilia dregeana Sond. bark | South Africa | [42] |
| Skin diseases | | | |
| Abscesses, chicken pox, eczema, purulent rashes, scabies and skin diseases | Bark, leaves and roots | Burundi, Cameroon, South Africa and Swaziland | [28, 33, 44, 47, 49, 52, 56–59] |
| Toothache | Leaves and roots | South Africa | [32] |
| Typhoid fever | Stem bark | Cameroon | [27] |
| Urinary problems | Stem bark | Cameroon | [27] |
| Wounds and pain | | | |
| Abdominal pains, back pain (lumbago) and anal wounds | Bark, leaves and stem bark | Cameroon, Guinea-Bissau and Mozambique | [27, 36, 50, 60] |
| Yaws | Root bark | Rwanda | [44] |
| Ethnoveterinary medicine | | | |
| Coccidiosis and wounds | Roots | Zimbabwe | [61, 62] |
| Ethnoveterinary medicine | Blisters treated with leaves mixed with those of Gynura scandens O. Hoffm. and fruits of Musa paradisiaca L. | DRC | [43] |
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