Factors Influencing Hemoglobin Variability and Its Association with Mortality in Hemodialysis Patients
Table 3
Demographic characteristics, biochemical parameters, and medications of patients.
Exitus (: 31)
Alive (: 138)
value
Age (years)
60.6 ± 20.0
53.4 ± 13.4
0.027
Gender (male)
27 (15.9%)
96 (56.8%)
0.248
Duration of hemodialysis (years)
7.6 ± 5.4
9.5 ± 5.7
0.121
Hemoglobin (g/dl)
10.6 ± 1.03
10.8 ± 1.2
0.530
Hb-var (g/dl)
0.94 (0.25)
0.89 (0.26)
0.578
Maximum Hb-var (g/dl)
3.2 (1.7)
3.3 (1.7)
0.565
Coefficient of Hb-var
8.8 (3.1)
8.4 (3.0)
0.429
RDW (%)
16.2 (1.6)
16.3 (2)
0.733
Leukocyte (×103/µl)
7.0 ± 1.7
6.6 ± 1.7
0.354
MCV (fl)
89.7 ± 4.9
90.1 ± 5.5
0.788
Serum Iron (mg/dl)
53.5 (16.3)
58.2 (23.2)
0.206
Transferrin saturation (%)
29.7 (11.7)
29.7 (18.3)
0.301
Ferritin (µg/l)
344.2 (297.7)
305.3 (317.1)
0.478
PTH (pg/ml)
252.1 (419)
415 (699)
0.092
Calcium (mg/dl)
9.1 ± 0.6
9.1 ± 0.7
0.988
Phosphate (mg/dl)
5.1 ± 1.2
5.2 ± 1.3
0.615
Albumin (g/dl)
4.0 ± 0.3
4.2 ± 0.4
0.150
CRP (mg/l)
16.7 (21.0)
8.2 (11.4)
0.008
URR (%)
66.5 ± 5.5
66.0 ± 6.6
0.693
MİS
8 (3)
6 (3)
0.002
ESA total dose per body weight (U/kg)
4.1 (2.3)
3.1 (3.8)
0.066
İron per body weight (mg/kg)
13.2 (23.1)
15.7 (21.5)
0.542
Months of hb < 11 g/dl
6.9 ± 3.1
6.2 ± 3.8
0.379
BMI (kg/m2)
21.0 ± 3.8
23.0 ± 4.5
0.046
10 year survival
2 (37)
21 (75)
0.011
HA: high-amplitude fluctuation; LAH: low-amplitude fluctuation with high hemoglobin; LAL: low-amplitude fluctuation with low hemoglobin; Hb-var (hemoglobin variability); MCV: mean corpuscular volume; RDW: red blood cell distribution width; CRP: C-reactive protein; PTH: parathyroid hormone; URR: urea reduction ratio; MIS: malnutrition-inflammation score; ESA: erythropoiesis-stimulating agents; BMI: body mass index, Median (interquartile range) other results are given as mean ± standard deviation.
