Chemical Composition, Antifungal, and Cytotoxicity Activities of Inga laurina (Sw.) Willd Leaves

Table 2

Results of antifungal activity (expressed as MIC in μg mL⁻¹), cytotoxic activity (expressed as CC₅₀ in μg mL⁻¹), and selectivity index for extract and fractions of I. laurina leaves.

	MIC (g mL^−1)
Microorganisms	EE	HF	CF	EAF	BF
C. albicans ATCC 28366	46.8	1,500	>3,000	93.8	11.7
C. glabrata ATCC 15126	11.7	187.5	>3,000	11.7	23.4
C. tropicalis ATCC 13803	93.8	3,000	>3,000	93.8	46.8
	CC50 (g mL^−1)
Vero cells	352 ± 5	384 ± 9	>512	>512	>512
	SI
Microorganisms	EE	HF	CF	EAF	BF
C. albicans ATCC 28366	0.9	- 0.6	> - 0.8	> 0.7	> 1.6
C. glabrata ATCC 15126	1.5	0.3	> - 0.8	> 1.6	> 1.3
C. tropicalis ATCC 13803	0.6	- 0.9	> - 0.8	> 0.7	> 1.0

EE = ethanol extract; HF = hexane fraction; CP = chloroform fraction; EAF = ethyl acetate fraction; BF = -butanol fraction. SI: selectivity index. ATCC: American Type Culture Collection.