Research Article

Macrophylloflavone: A New Biflavonoid from Garcinia macrophylla Mart. (Clusiaceae) for Antibacterial, Antioxidant, and Anti-Type 2 Diabetes Mellitus Activities

Table 4

A total number of cells on histology of kidney, pancreas, and liver of rats in various groups.

TreatmentHistology of rat kidneyHistology of rat pancreasHistology of rat liver
Normal cells of tubules (cells ± SD)Necrosis cells of tubules (cells ± SD)Beta cells of pancreatic (cells ± SD)Normal cells of hepatocyte (cells ± SD)Necrosis cells of hepatocyte (cells ± SD)

A382 ± 8.72a103 ± 12.49e286 ± 13.00a298 ± 8.19a75 ± 9.17d
B0299 ± 13.53c162 ± 4.36a184 ± 8.00d262 ± 13.08c113 ± 6.56a
B1328 ± 17.35b136 ± 7.94bc252 ± 7.81c281 ± 9.54ab91 ± 4.58bc
B2285 ± 15.09c154 ± 14.00ab241 ± 7.21c276 ± 10.00bc102 ± 12.17ab
B3343 ± 5.29b127 ± 6.24cd269 ± 9.64b284 ± 7.81ab86 ± 6.08cd
B4374 ± 10.44a112 ± 14.93de280 ± 7.00ab287 ± 4.36ab78 ± 8.54cd

A: the blank control, B0: the negative control, B1: the positive control, B2: the compound 1 given at a dose of 6 μg/kg body weight, B3: the compound 1 given at a dose of 7 μg/kg body weight, B4: the compound 1 given at a dose of 8 μg/kg body weight. Different letters showed significant differences between the groups ().