Hepatoprotective Effects of a Novel Trihoney against Nonalcoholic Fatty Liver Disease: A Comparative Study with Atorvastatin

Table 2

Baseline (week 0) and final (week 12) serum liver function test.

Parameters

Groups

C

C + H

HCD

HCD + H1

HCD + H2

HCD + At.

Week 0

Week 12

Week 0

Week 12

Week 0

Week 12

Week 0

Week 12

Week 0

Week 12

Week 0

Week 12

Total Bil. (µmol/L)

2.33 ± 1.37

4.00 ± 2.09

3.17 ± 2.79

3.17 ± 1.47

3.83 ± 1.94

16.17 ± 5.23

3.00 ± 3.16

4.67 ± 2.73

3.67 ± 2.66

12.67 ± 7.23

3.17 ± 2.71

25.33 ± 29.69

ALP (U/L)

160.50 ± 126.48

93.67 ± 30.22

95.33 ± 35.43

73 ± 37.87

77.17 ± 29.34

73.83 ± 37.49

142.83 ± 78.85

49.67 ± 29.04

134.17 ± 34.59

55.50 ± 13.09

98.50 ± 23.17

52.17 ± 26.33

GGT (U/L)

10.67 ± 3.56

12.17 ± 0.98

10.00 ± 2.00

10.83 ± 6.15

9.00 ± 2.45

14.83 ± 3.31

10.67 ± 3.98

5.83 ± 2.14^d

12.17 ± 4.49

13.50 ± 8.41

10.50 ± 2.95

24.17 ± 22.39

AST (U/L)

48.67 ± 18.75

55.67 ± 21.23

50.67 ± 12.61

51.17 ± 24.74

49.50 ± 15.86

200.00 ± 64.56^a, b

62.33 ± 22.43

62.33 ± 48.09^c

52.00 ± 12.44

48.83 ± 35.39^c

39.33 ± 11.74

56.17 ± 47.66^c

ALT (U/L)

66.17 ± 22.78

71.50 ± 36.69

53.50 ± 19.85

41.83 ± 8.30

60.67 ± 7.45

180.17 ± ^, b

59.83 ± 17.01

56.83 ± 50.19^c

64.83 ± 14.82

48.83 ± 26.51^c

43.83 ± 14.99

55.50 ± 36.31^c

Values are mean ± standard deviation (SD) of the mean. The results of all experiment groups were analysed using one-way analysis of variance (ANOVA), followed by the Tukey HSD post hoc test. Mean difference is considered significant at .ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALP, alkaline phosphatase; GGT, gamma-glutamyl transferase; T. Bil., total bilirubin. ^aSignificant different from the C group; ^bsignificant different from the C + H group; ^csignificant different from the HCD group; ^dsignificant different from HCD + At. ; ; ].