The Scientific World Journal

Review Article

Herbal Medicinal Products from Passiflora for Anxiety: An Unexploited Potential

Table 3

List of ANVISA registered products containing Passiflora sp.


Product/category	Dosage form	Manufacturer Code	Status	Active

A SAÚDE DA MULHER/antispasmodic, anticholinergic, drug combination	Oral solution	57.507.378/0003-65	Valid	Sodium salicilate/Passiflora alata Curtis (fluid extract)/‘Agoniada pluméria’ (tincture)/bitter orange peel (fluid extract)
A SAÚDE DA MULHER/antispasmodic, anticholinergic, drug combination	Simple dragee/oral solution	45.992.062/0001-65	Canceled	Sodium salicilate/Passiflora dry extract/‘Agoniada’ dry extract
ACALMIL/herbal compound	Coated tablet	29.333.218/0001-40	Canceled	Passiflora incarnata L./Salix alba L. (leaves extract)/Crataegus oxyacantha L. extract
ACALMIL/herbal compound	Coated tablet	92.265.552/0001-40	Canceled	Passiflora incarnata L./Salix alba L. (leaves extract)/Crataegus oxyacantha L. extract
ALPHALIV/simple Herbal, simple anxiolytic	Oral solution/coated tablet	09.545.589/0001-88	Valid	Passiflora incarnata L.
ANSIODORON/potentized preparation	Tablet	56.992.217/0001-80	Valid	Avena sativa L./Passiflora alata Curtis/Valeriana officinalis L
BRONQUIOGEN/herbal compound	Oral solution	51.603.488/0001-82	Canceled	Caesalpinia ferrea Mart. /Roripa nasturtium Beck/Mikania glomerata Spreng./ Lantana camara L./Passiflora alata Curtis/Melissa officinalis L./Myrospermum erythroxylum Allem
CALMAN/herbal compound	Coated tablet/oral solution	02.433.631/0001-20	Valid	Crataegus rhipidophylla Gand./Passiflora incarnata L./Salix alba L.
CALMAN/herbal compound	Coated tablet/oral solution	64.088.172/0001-41	Canceled	Crataegus rhipidophylla Gand./Salix alba L./Passiflora incarnata L.
CALMANTE FARMAERVAS/herbal compound	Oral solution	60.565.520/0001-73	Canceled	Melissa officinalis L./Passiflora alata Curtis /Valeriana officinalis L./Lavandula officnalis Chaix
CALMAPAX/similar, associated natural products	Coated tablet/oral solution /cropped	33.173.097/0002-74	Canceled	Passiflora incarnata L./Erythrina mulungu Mart./Matricaria chamomilla L./ Melissa officinalis L. (only in oral solution)
CALMASYN/simple herbal, simple analytic	Oral solution/coated tablet	17.562.075/0001-69	Valid	Passiflora incarnata L.
CALMAVITA/simple herbal	Hard gelatin capsule	56.646.953/0001-86	Canceled	Passiflora incarnata L.
CALMI/herbal compound	Oral solution	17.299.140/0001-05	Canceled	Matricaria chamomilla L./Citrus aurantium L./Cymbopogon citratus Stapf/ Passiflora alata Curtis
ACALMIL/herbal compound	Syrup	06.597.801/0001-62	Valid	Passiflora incarnata L.
CALMIPLAN/herbal compound	Coated tablet	47.100.862/0001-50	Canceled	Passiflora incarnata L./Salix alba L./Crataegus rhipidophylla Gand.
CALMOPLANTAS/simple herbal, simple anxiolytic	Tincture/hard gelatin capsule	79.634.572/0001-82	Valid	Passiflora incarnata L./Salix alba L./Crataegus rhipidophylla Gand.
CALMOXIL/simple herbal, simple anxiolytic	Coated tablet/oral solution	28.643.633/0001-37	Canceled	Passiflora incarnata L.
CARDIOPAX GOTAS/Homeopathic association	Oral solution	76.440.528/0001-43	Canceled	Passiflora incarnata L./Crataegus rhipidophylla Gand./Digitalis sp.
CARDIOSETYL M/simple herbal, simple anxiolytic	Oral solution	21.573.449.0001-19	Canceled	Passiflora incarnata L.
CARDIOSETYL M/herbal compound/antispasmodic	Oral solution	21.573.449/0001-19	Canceled	Passiflora alata Curtis/Crataegus rhipidophylla Gand./Erythrina mulungu Mart./ Leptolobio elegans Vog
DALAY/simple herbal	Coated tablet/oral solution	01.858.973/0001-29	Valid	Passiflora dry extract
DYRAJAIA/herbal compound	Tincture	02.007.074/0001-85	Canceled	Passiflora alata Curtis/Dorstenia multiformis Miq.
ELIXIR DE MARACUJÁ COMPOSTO FARMAERVAS/herbal compound	Elixir	60.565.520/0001-73	Canceled	Passiflora alata Curtis /Paullinia cupana Kunth/ Valeriana officinalis L.
EQUILIBRISSE/simple herbal, simple anxiolytic	Coated tablet	05.161.069/0001-10	Valid	Passiflora dry extract
EQUILIBRISSE/simple herbal, simple anxiolytic	Coated tablet	05.161.069/0001-10	Valid	Passiflora incarnata L.
ELIXIR DE CEREUS COMPOSTO/herbal compound	Oral solution	92.695.816/0001-03	Canceled	Crataegus tincture/Cereus grandiflorus (L.) Mill./Valeriana officinalis L./Passiflora alata Curtis
ERVA SILVINA COMPOSTA/herbal compound	Elixir	92.943.992/0001-09	Canceled	Casearia sylvestris Sw./Aristolochia cymbifera Martius/Passiflora alata Curtis
FIMATOSAN/Associated natural products	Oral solution	33.379.887/0001-96	Canceled	Caesalpinia ferrea Mart./Roripa nasturtium Beck/Mikania glomerata Spreng./Passiflora alata Curtis/Polypodium vulgare/Myrospermum erythroxylum Allem./Lantana camara Linné
FIQUEZEN/simple herbal, simple anxiolytic	Coated tablet/oral solution	17.875.154/0001-20	Valid	Passiflora dry extract
FITOCALM/simple herbal, simple anxiolytic	Coated tablet	84.684.620/0001-87	Valid	Passiflora incarnata L.
FITOCALMIN/simple herbal	Hard gelatin capsule	14.186.324/0001-70	Canceled	Passiflora incarnata L.
FLORINY/Anxiolytics—drug combination/herbal compound	Coated tablet/oral solution	64.088.172/0001-41	Canceled	Passiflora incarnata L./Salix alba L./Crataegus oxyacantha L.
MARACUGINA COMPOSTA/herbal compound/anxiolytic	Oral solution/coated tablet	61.082.426/0002-07	Canceled	Erythrina mulungu Mart./Crataegus rhipidophylla Gand./Passiflora alata Curtis
MARACUGINA COMPOSTA/herbal compound	Oral solution/coated tablet	67.866.665/0002-34	Canceled	Passiflora alata Curtis/Erythrina mulungu Mart./Crataegus rhipidophylla Gand.
MARACUGINA COMPOSTA/herbal compound	Oral solution/coated tablet	02.932.074/0001-91	Canceled	Passiflora alata Curtis/Erythrina mulungu Mart./Crataegus rhipidophylla Gand.
MARACUGINA PI/ simple herbal, simple anxiolytic	Coated tablet	61.082.426/0002-07	Valid	Passiflora dry extract
MARACUGINA PI/ simple herbal, simple anxiolytic	Coated tablet	61.082.426/0002-07	Valid	Passiflora incarnata L.
MARACUJÁ CONCENTRIX/herbal compound, simple anxiolytic	Simple dragees/oral solution	05.044.984/0001-26	Canceled	Crataegus rhipidophylla Gand./Passiflora incarnata L./Salix alba L.
MARACUJÁ GOTAS/simple herbal	Hydroalcoholic solution	78.950.011/0001-20	Canceled	Passiflora incarnata L.
MARACUJÁ HERBARIUM/simple herbal, simple anxiolytic	Hard gelatin capsule/coated tablet	78.950.011/0001-20	Valid	Passiflora incarnata L.
MULUNGU BROMETADO/similar	Syrup	10.419.935/0001-60	Canceled	KBr/NaBr/ NH4Br/Atropa belladonna tincture/Hyosciamus niger L. Tincture/Passiflora alata Curtis
NERVITON/Associated phytotherapics	Elixir	92.751.965/0001-34	Canceled	Passiflora alata Curtis/Ptychopetalum olacides Benth/Cola nitida Schott & Endl./Paullinia cupana Kunth/thiamine hydrochloride
NEUREXAN/Dynamized compound	Sublingual tablet	05.994.539/0001-27	Valid	Avena sativa L./ Coffea arabica L./ Passiflora incarnata L./Zincum isovalerianicum
NUIT/herbal compound	Coated tablet	49.475.833/0001-06	Canceled	Passiflora incarnata L./ Valeriana officinalis L./Crataegus rhipidophylla Gand.
PASALIX/herbal compound	Coated tablet	60.726.692/0001-81	Valid	Crataegus rhipidophylla Gand./Passiflora incarnata L./Salix alba L.
PASALIX PI/simple herbal, simple anxiolytic	Coated tablet/oral solution	60.726.692/0001-81	Valid	Passiflora incarnata L.
PASIC/herbal compound	Coated tablet/oral aerosol	44.734.671/0001-51	Canceled	Passiflora incarnata L./ Crataegus rhipidophylla Gand./Salix alba L.
PASSANEURO/herbal compound	Coated tablet	47.100.862/0001-50	Canceled	Passiflora dry extract/ Erithrina mulungu Mart./Matricaria chamomilla L.
PASSICALM/herbal compound	Oral solution	85.776.524/0001-21	Canceled	Erithrina mulungu Mart./Valeriana officinalis L./ Passiflora alata Curt
PASSIENE/simple herbal	Syrup	78.950.011/0001-20	Canceled	Passiflora dry extract
PASSIENE/simple herbal	Syrup/ coated tablet	78.950.011/0001-20	Valid	Passiflora incarnata L.
PASSIFLORA/herbal compound	Tincture	02.007.074/0001-85	Canceled	Passiflora dry extract/ Erithrina mulungu Mart.
PASSIFLORA ALTHAIA/simple herbal, simple anxiolytic	Oral solution	48.344.725/0007-19	Valid	Passiflora incarnata L.
PASSIFLORA CATARINENSE/simple herbal, simple anxiolytic	Coated tablet	84.684.620/0001-87	Valid	Passiflora incarnata L.
PASSIFLORA COMPOSTA/herbal compound	Oral solution/ simple dragee	42.341.149/0001-84	Canceled	Crataegus rhipidophylla Gand./Passiflora incarnata L./Eerythrina mulungu Mart.
PASSIFLORA COMPOSTA/herbal compound	Elixir	61.299.111/0001-35	Canceled	Erythrina mulungu Mart./Melissa officinalis L./Passiflora alata Curtis
PASSIFLORA DA ÍNDIA/associated natural products	Elixir	87.104.170/0001-02	Canceled	Passiflora alata Curtis/ Atropa belladonna L./ Erythrina mulungu Mart./Citrus limetta Risso/Cereus grandiflorus (L.) Mill.
PASSIFLORA KLEIN/simple herbal, simple anxiolytic	Tincture	92.762.277/0001-70	Valid	Passiflora incarnata L.
PASSIFLORA ORIENT/simple herbal	Hard gelatin capsule	73.657.876/0001-89	Canceled	Passiflora incarnata L.
PASSIFLORINE/herbal compound	Oral solution/simple dragee	33.388.182/0001-79	Canceled	Passiflora incarnata L./Salix alba L./Crataegus rhipidophyla Gand./Calcium gluconate/Cholecalciferol/low molecular weight peptides/magnesium hyposulfium
PASSIFLORINE PI/simple herbal, simple anxiolytic	Coated tablet	23.668.196/0001-92	Valid	Passiflora dry extract
PASSIPAX/simple herbal	Oral solution	04.656.253/001-79	Valid	Passiflora incarnata L.
PAZINE/simple herbal, simple anxiolytic	Coated tablet	64.088.172/0001-41	Canceled	Passiflora incarnata L.
PAZINE/simple herbal, simple anxiolytic	Coated tablet	07.670.111/0001-54	Valid	Passiflora incarnata L.
PHYTOCALM /herbal compound	Syrup/hard gelatin capsule	84.684.620/0001-87	Canceled	Passiflora incarnata L./Valeriana officinalis L./Matricaria chamomilla L./Crataegus oxyacantha L./Erythrina mulungu Mart.
PRAKALMAR/Simple herbal, simple anxiolytic	Coated tablet	02.433.631/0001-20	Valid	Passiflora incarnata L.
PRASILENCE/Simple herbal, simple anxyolitic	Oral solution/coated tablet	25.773.037/0001-83	Valid	Passiflora incarnata L.
RITMONEURAN/Herbal compound	Hard gelatin capsule/oral solution	92.695.691/0001-03	Canceled	Passiflora alata Curtis/Erythrina mulungu Mart./Leptolobio elegans Vog/Adonis vernalis L.
RITMONEURAN RTM/simple anxiolytic, simple herbal	Hard gelatin capsule/oral solution/ coated tablet	92.695.691/0001-03	Valid	Passiflora dry extract
SALSAPARILHA COMPOSTO/Associated natural products	Elixir	92.943.992/0001-09	Canceled	Smilax japicanga Griseb./Baccharis genistelloides Persoon/Plantago major L./Aristolochia cymbifera Martius/Passiflora incarnata L.
SEAKALM/herbal compound	Coated tablet	02.456.955/0001-83	Canceled	Passiflora incarnata L./Salix alba L./Crataegus rhipidophylla Gand.
SEAKALM/simple anxiolytic, simple herbal	Coated tablet/oral solution	02.456.955/0001-83	Valid	Passiflora incarnata L.
SEDACAL/ simple herbal	Hard gelatina capsule	01.845.448/0001-79	Canceled	Passiflora incarnata L.
SEDANUS/associated natural products	Oral solution	67.866.665/0002-34	Canceled	Crataegus oxyacantha L./Passiflora incarnata L./Erythrina mulungu Mart.
SERENUS/associated phytotherapics	Coated tablet	49.475.833/0001-06	Valid	Crataegus rhipidophylla Gand./Passiflora incarnata L./Salix alba L.
SINTOCALMY/simple herbal simple anxiolytic	Coated tablet	60.659.463/0001-91	Valid	Passiflora incarnata L.
SOMINEX/herbal compound	Tablet	57.507.378/0001-01	Canceled	Crataegus rhipidophylla Gand./Valeriana officinalis L./Passiflora incarnata L.
SOMINEX COMPOSTO/herbal compound anxiolytics—drug combinations	Coated tablet	57.507.378/0001-01	Canceled	Valeriana officinalis L./Crataegus rhipidophylla Gand./ Passiflora incarnata L.
SONOTABS/herbal compound	Simple dragee	92.695.691/0001-03	Canceled	Passiflora dry extract/Salix dry extract/Crataegus rhipidophylla Gand. extract
SONOTABS/herbal compound	Simple dragee	90.455.262/0001-33	Canceled	Passiflora dry extract/Salix dry extract/Crataegus rhipidophylla Gand. extract
SPASCUPREEL/potentized compound	Sublingual tablet/injectable solution	05.994.539/0001-27	Valid	Aconitum napellus L./ Ammonium bromatum/Agaricus muscarius/Citrullus colocynthis Schrad./Colocynthis/Gelsemium sempervirens (L.) J. St.-Hil./ Magnesium phosphoricum/Matricaria recutita L./ Passiflora incarnata L./ Veratrum album L./ Atropinum sulfuricum/Cuprum suphuricum
SPASCUPREEL/potentized compound	Sublingual tablet/	74.455.197/0001-90	Canceled	Atropinum sulfuricum/Citrullus colocynthis Schrad./Veratrum album L./ Magnesium phosphoricum/Gelsemium sempervirens (L.) J. St.-Hil./ Passiflora incarnata L./ Agaricus muscarius/Chamomilla recutita/Aconitum napellus
TENSART/simple herbal	Coated tablet/oral solution	64.088.172/0001-41	Canceled	Passiflora incarnata L.
TENSART/ simple herbal	Coated tablet/oral solution	17.440.261/0001-25	Valid	Passiflora incarnata L.

Source: https://consultas.anvisa.gov.br/#/medicamentos/. Accessed on December 03, 2019.