Regenerative Endodontic Therapy in the Management of Immature Necrotic Permanent Dentition: A Systematic Review

Table 3

Quality and risk Assessment of all the included studies in this systematic review.

Study (year)	Random sequence generation	Allocation concealment	Defined inclusion/exclusion	Blinding of outcome assessment	Incomplete outcome data	Selective reporting	Other sources of bias
Alasqah et al. [26] (2020)	+	+	+	+	+	+	+
Rizk et al. [27] (2019)	+	+	+	+	+	?	+
Ajram et al. [28] (2019)	+	+	+	+	+	+	+
Ulusoy and Cehreli [29] (2017)	+	+	+	?	+	+	?
Moodley et al. [30] (2017)	?	+	+	+	+	+	+
Timmerman and Parashos [31] (2017)	+	+	+	+	+	+	+
Bakhtiar et al. [32] (2017)	+	+	+	+	+	+	+
Altaii et al. [33] (2017)	+	+	+	+	+	+	+
Saoud et al. [34] (2015)	+	+	+	+	?	+	+
Nosrat et al. [35] (2015)	?	?	+	+	+	+	+
Torabinejad et al. [36] (2015)	+	+	+	+	+	+	+
Londero Cde et al. [37] (2015)	+	+	+	+	+	?	?
Rodríguez-Benítez et al. [38] (2015)	+	+	+	+	+	+	+
Bezgin et al. [39] (2015)	+	+	+	+	+	+	+
Narang et al. [40] (2015)	+	+	+	+	+	+	+
Saoud et al. [4] (2014)	+	+	+	+	+	+	+
Khademi et al. [41] (2014)	+	+	+	+	+	+	+
Yoo et al. [42] (2014)	+	+	+	+	+	+	+
Zhang et al. [43] (2014)	+	+	+	+	+	+	+
Alobaid et al. [44] (2014)	+	+	+	+	+	+	+
Nagata et al. [45] (2014)	+	+	+	+	+	+	+
Kahler et al. [46] (2014)	+	+	+	+	+	+	+
Nagy et al. [47] (2014)	+	+	+	+	+	+	+
Tawfik et al. [48] (2013)	+	+	+	+	?	+	?
Zhu et al. [49] (2013)	+	+	+	+	+	?	+
Jadhav et al. [50] (2013)	+	+	+	+	+	+	+
Sönmez et al. [51] (2013)	+	+	+	+	+	+	+
Mc Tigue et al. [52] (2013)	+	+	+	+	+	+	+
Martin et al. [53] (2013)	+	+	+	+	+	+	+
Petrović et al. [54] (2013)	+	+	+	+	+	+	+
Dabbagh et al. (2012) [55]	+	+	+	+	+	+	+
Chen et al. [3] (2012)	+	+	+	+	+	+	+
Jeeruphan et al. [6] (2012)	+	+	+	+	+	+	+
Kim et al. [56] (2012)	+	+	+	+	+	+	+
Iwaya et al. [57] (2011)	+	+	+	+	+	+	+
Torabinejad and Turman [20] (2011)	+	+	+	+	+	+	+
Cehrelli et al. [16] (2011)	+	+	+	+	+	+	+
Yamauchi et al. [58] (2011)	+	+	+	+	+	+	+
Nosrat et al. [59] (2011)	+	+	+	+	+	+	+
Petrino et al. [60] (2010)	+	+	+	+	+	+	+
Zuong et al. [61] (2010)	+	+	+	+	+	+	+
Da Silva et al. [62] (2010)	+	+	+	+	+	+	+
Thomson and Kahler [63] (2010)	+	+	+	+	+	+	+
Reynolds et al. [22] (2009)	+	+	+	+	+	+	+
Ding et al. [64] (2009)	+	+	+	+	+	+	+
Bose et al. [65] (2009)	+	+	+	+	?	?	+

+ = low risk; ? = unclear risk; and − = high risk.