Research Article

Biophysical Insight into the Interaction of Human Lysozyme with Anticancer Drug Anastrozole: A Multitechnique Approach

Table 1

Binding parameters of anastrozole interaction to HL in 20 mM phosphate buffer of pH 7.4 at 310 K temperature obtained and calculated from fluorescence quenching data.

T (K)Ksv (×103 M−1)R2Kq (×1012 M−1s−1)Kb (×103 M−1)R2nΔG (kcal·mol−1)ΔH (kcal·mol−1)ΔS (cal.·mol−1·K−1)

3109.200.999.209.660.991.00−5.65−11.15−19.30