In Vitro Antibacterial Activity of Crude Extracts of Artocarpus heterophyllus Seeds against Selected Diarrhoea-Causing Superbug Bacteria

Table 3

Mean and standard error of mean inhibition zone diameters of the ethanolic and hexane crude extract of A. heterophyllus seeds against selected bacteria causing diarrhoea.

Mean inhibition zone diameter ± SEM (mm)
Test bacteria
	MRSA	MSSA	S. typhimurium	MDR PA	R E. coli
Ethanolic extract
1000 mg/ml	15.0 ± 1.0	15.0 ± 2.0	0	11.0 ± 1.0	0
500 mg/ml	16.5.25	16.5 ± 0.5	0	8.5 ± 0.5	0
Hexane extract
1000 mg/ml	16.5 ± 0.5	16.0 ± 1.0	0	9.0 ± 1.0	0
500 mg/ml	15.5 ± 0.5	14.5 ± 0.5	0	10.5 ± 0.5	0
Controls
Ceftriaxone, 15 μg/mL (+ve)	0	30.5 ± 2.5	33.0 ± 1.0	20.0 ± 1.0	27.0 ± 1.0
Vancomycin, 30 μg/mL (+ve)	12.5 ± 0.5	14.5 ± 0.5	ND	ND	ND
10% DMSO (−ve)	0	0	0	0	0

Key: MRSA: methicillin-resistant Staphylococcus aureus, MSSA: methicillin-susceptible Staphylococcus aureus, S. typhimurium: ciprofloxacin-resistant S. typhimurium, MDR PA: multidrug-resistant P. aeruginosa, R E. coli: third-generation cephalosporin-resistant E. coli. Different super indexes of an asterisk (, and ) in each column of bacteria show a significant difference ( < 0.05) within different extract concentration and also between controls, ND: not done.