Treadmill Exercise Training Ameliorates Functional and Structural Age-Associated Kidney Changes in Male Albino Rats
Table 1
Weight (body and kidney) and biochemical parameters of the different groups.
Parameter
Young
Sedentary aged
Exercised aged
Weight
Body weight (g)
187 ± 10.0
430 ± 12.4
405 ± 10.0##
Relative kidney weight (g/100 g body weight)
0.54 ± 0.03
0.52 ± 0.01
0.53 ± 0.02
Kidney function tests
Plasma creatinine (mg/dL)
0.72 ± 0.06
0.82 ± 0.06
0.77 ± 0.06
Plasma urea (mg/dL)
40.2 ± 1.8
53.6 ± 5.2
45.3 ± 7.1#
Plasma cystatin C (mg/L)
0.91 ± 0.15
2.5 ± 0.28
1.6 ± 0.42##
Creatinine clearance (mL/min)
1.27 ± 0.10
0.94 ± 0.06
1.02 ± 0.5
Oxidative/antioxidative markers
MDA (nmoL/mL)
5.14 ± 0.99
11.39 ± 1.75
8.96 ± 1.60#
TAC (nmoL/L)
2.49 ± 0.12
2.14 ± 0.17
2.44 ± 0.07##
Inflammatory markers
CRP (mg/L)
3.20 ± 0.78
8.00 ± 1.56
5.20 ± 0.78##
IL-6 (pg/mL)
148 ± 12.2
161 ± 8.9
152 ± 11.0
Values are presented as mean ± SD (n = 10). ∗indicates ;∗∗indicates compared with young group; #indicates ;##indicates compared with sedentary aged group. MDA: malondialdehyde. TAC: total antioxidant capacity. CRP: C-reactive protein. IL-6: interleukin-6.
