Synthesis and Evaluation of the Acetylcholinesterase Inhibitory Activities of Some Flavonoids Derived from Naringenin

Figure 1

Alignment of docked pose of compound 7 with galantamine as cocrystallized ligand in the AChE complex (PDB ID: 1W6R). Compound 7 is rendered in cornflower blue, and galantamine is rendered in red. Asp, aspartate; Trp, tryptophan; Gly, glycine; Tyr, tyrosine; Glu, glutamate; Ser, serine; Phe, phenylalanine; His, histidine; Ile, isoleucine.