Research Article

Predicting the Most Deleterious Missense Nonsynonymous Single-Nucleotide Polymorphisms of Hennekam Syndrome-Causing CCBE1 Gene, In Silico Analysis

Table 1

Genes coexpressed and sharing a domain with CCBE1.

Gene symbolDescriptionCoexpressionShared domain

COL6A6Collagen type VI alpha 6YesNo
MXRA8Matrix remodeling associated 8YesNo
PLEKHF2Pleckstrin homology and FYVE domain containing 2YesNo
RPRMReprimo, TP53 dependent G2 arrest mediator candidateYesNo
CDH4Cadherin 4NoNo
PLEKHG1Pleckstrin homology and RhoGEF domain containing G1YesNo
CAND1Cullin associated and neddylation dissociated 1YesNo
MYO10Myosin XYesNo
LRRC4CLeucine rich repeat containing 4CYesNo
LRATLecithin retinol acyltransferaseYesNo
ANK3Ankyrin 3, node of RanvierYesNo
OLFM1Olfactomedin 1YesNo
DCNDecorinYesYes
NEURL1BNeuralized E3 ubiquitin protein ligase 1BYesNo
PLEKHH2Pleckstrin homology, MyTH4, and FERM domain containing H2YesYes
GLTSCR2Glioma tumor suppressor candidate region gene 2YesNo
NDRG2NDRG family member 2YesNo