Seroprevalence of Hepatitis C Viral Infection in Ethiopia: A Systematic Review and Meta-Analysis

Table 1

Characteristics of the included studies in the systematic review and meta-analysis for the prevalence of anti-HCV in Ethiopia, 2020.

First author, publication year [reference]	Region	Study group	Sampling technique	Sample	Positive	Diagnostic method	Risk of bias
Abate and Wolde, 2016 [36]	Somali	Blood donors	Consecutive	6827	99	ELISA	Moderate
Abebe et al., 2020 [78]	Oromia	Blood donors	Consecutive	17810	114	ELISA
Abera et al., 2017 [37]	Amhara	Adult population	Random	481	5	RDT	High
Abera et al., 2014 [38]	Amhara	HIV	Random	253	14	ELISA	Moderate
Abdella et al., 2020 [77]	Nation-wide	Blood donors	Random	554954	2220	ELISA
Alemayehu et al., 2011 [39]	SNNPR	Mixed	Consecutive	800	66	ELISA	Moderate
Ameha et al., 2019 [76]	Amhara	VCT	Random	382	8	RDT	Moderate
Amsalu et al., 2016 [40]	SNNPR	Mixed	Entire	234	2	RDT	High
Anagaw et al., 2012 [18]	Amhara	Mixed	Not stated	200	1	RDT	High
Asemahagn, 2020 [79]	Amhara	Surgical	Random	422	18	RDT
Assefa et al., 2013 [41]	Amhara	Blood donors	Entire	2384	15	ELISA	Moderate
Ataro et al., 2018 [42]	SAC	Blood donors	Entire	6376	61	ELISA	Low
Atsbaha et al., 2016 [43]	Tigray	Mixed	Random	302	13	RDT	Low
Ayano et al., 2020 [80]	SAC	Psychiatric	Random	309	4	ELISA
Ayele and Gebre-Selassie, 2013 [25]	SAC	Liver disease	Convenient	120	27	RDT	High
Ayele et al., 2020 [81]	Gambella	Refugees	Convenient	453	9	ELISA
Azerefegn et al., 2018 [73]	SNNPR	Blood donors	Entire	6849	48	ELISA	Low
Bafa and Egata, 2019 [82]	SNNPR	Pregnant women	Random	222	4	ELISA
Balew et al., 2014 [44]	Amhara	HIV	Random	395	5	RDT	Low
Berhanu S, 2018 [74]	Amhara	Blood donors	Entire	7255	49	ELISA	Moderate
Biadgo et al., 2017 [45]	Amhara	Blood donors	Entire	6471	51	ELISA	Low
Birhaneselassie et al., 2016 [46]	SNNPR	Blood donors	Entire	6337	38	ELISA	Moderate
Birku T, 2015 [19]	Amhara	Military personnel	Random	403	1	RDT	Low
Bisetegen et al., 2016 [47]	SNNPR	Blood donors	Consecutive	390	33	ELISA	Moderate
Dabsu Ejeta, 2018 [48]	Oromia	Pregnant women	Convenient	421	34	RDT	Low
Dagnew M, 2020 [83]	Amhara	Pregnant women	Random	1121	18	ELISA
Demsiss et al., 2018 [49]	Amhara	Health students	Random	408	3	ELISA	Low
Deressa et al., 2018 [20]	Amhara	Blood donors	Entire	8460	27	ELISA	Low
Ejeta and Dabsu, 2019 [50]	Oromia	Pregnant women	Consecutive	421	34	ELISA	Low
Gebrekristos et al., 2018 [51]	Tigray	Mixed	Not stated	460	77	ELISA	High
Hadush et al., 2013 [52]	Tigray	Mixed	Not stated	300	18	ELISA	High
Hebo et al., 2019 [21]	Oromia	Health workers	Random	240	1	ELISA	Low
Heyredin et al., 2019 [53]	Mixed	Blood donors	Consecutive	500	5	ELISA	Low
Juhar et al., 2018 [54]	SAC	Hemodialysis	Not stated	253	7	ELISA	High
Kebede et al., 2017 [55]	Oromia	Prisoner	Random	156	4	ELISA	Moderate
Manyazewal et al., 2014 [56]	SAC	Mixed	Not stated	500	18	ELISA	Low
Mekonnen et al., 2015 [57]	SAC	Waste handlers	Random	252	4	ELISA	Low
Metaferia et al., 2018 [58]	Amhara	Pregnant women	Consecutive	385	5	RDT	Low
Million et al., 2019 [75]	Amhara	Mixed	Convenient	610	30	ELISA	Low
Mohammed and Bekele, 2016 [22]	Somali	Blood donors	Entire	4224	17	ELISA	Moderate
Molla et al., 2015 [23]	Amhara	Pregnant women	Random	384	1	RDT	Low
Mulu et al., 2013 [59]	Amhara	HIV	Not stated	269	8	ELISA	High
Negash et al., 2019 [60]	Amhara	Blood donors	Consecutive	310	13	ELISA	Low
Seid et al., 2014 [61]	Amhara	Pregnant women	Random	385	8	RDT	Low
Shiferaw et al., 2019 [62]	Amhara	Blood donors	Entire	35435	213	ELISA	Low
Shimelis et al., 2019 [63]	SNNPR	HIV	Not stated	477	15	RDT	Low
Taye et al., 2019 [64]	SNNPR	Surgery patients	Random	422	23	RDT	Moderate
Taye et al., 2014 [65]	SNNPR	Chronic hepatitis	Not stated	220	8	RDT	High
Taye and Lakew, 2013 [66]	SAC	HIV	Nonprobability	387	25	RDT	Moderate
Teklemariam et al., 2018 [67]	Harari	Blood donors	Entire	11382	91	ELISA	Low
Tesfa et al., 2013 [68]	Amhara	General	Entire	2684	332	RDT	Moderate
Tessema et al., 2010 [69]	Amhara	Blood donors	Consecutive	6361	45	ELISA	Low
Tigabu et al., 2019 [70]	Amhara	Blood donors	Entire	5983	96	ELISA	Low
Wondimeneh et al., 2013 [71]	Amhara	HIV	Not stated	400	18	RDT	Low
Yami et al., 2011 [24]	Oromia	Blood donors	Random	6063	10	ELISA	Low
Zenebe et al., 2015 [72]	Amhara	Pregnant women	Nonprobability	318	2	ELISA	Moderate

SAC, self-administrative cities (Addis Ababa and/or Dire Dawa); ELISA, enzyme-linked immunosorbent assay; RDT, rapid diagnostic test; SNNPR, Southern Nations, Nationalities and Peoples Region; HIV, human immune virus; VCT, voluntary counseling and testing.