Comparative Study of Antiproliferative Activity in Different Plant Parts of Phaleria macrocarpa and the Underlying Mechanism of Action

Figure 5

DNA fragmentation of T47D cells treated different parts of P. macrocarpa for 24 and 48 h. (a). Pericarp; (b) seed; (c) mesocarp; (d) leaves. From left lane: M (DNA ladder 1 kb), C (untreated control cells), Cis (treated cells with 1 µg/mL of cisplatin), Lane 1–3 (treated cells with different concentrations (IC₅₀, 2x IC₅₀/2-fold of IC₅₀, and 4x IC₅₀/4-fold of IC₅₀) for 24 h, and Lane 4–6 (treated cells with different concentrations (IC₅₀, 2x IC₅₀/2-fold of IC₅₀, and 4x IC₅₀/4-fold of IC₅₀) for 48 h.

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