Diagnostic Performance of Three ELISAs for Detection of Antibodies against SARS-CoV-2 in Human Samples

Table 1

The overall diagnostic performance of enzyme-linked immunoassay (ELISA) performed with the N protein, S protein, and receptor binding domain (RBD) fraction as antigens.

Parameters	N protein	S protein	RBD
Sensitivity	0.99 (0.92–1.0)	0.91 (0.82–0.96)	0.87 (0.77–0.94)
Specificity	0.98 (0.92–1.0)	0.98 (0.92–1.0)	0.99 (0.94–1.0)
Accuracy	0.98 (0.95–1.0)	0.95 (0.90–0.98)	0.94 (0.89–0.97)

Values and the respective 95% confidence interval are in parentheses. Sensitivity = (True positive/(True positive + False negative)); Specificity = (True negative/(True negative + False positive)); Accuracy = ((True negative + True positive)/Total tests).