Pharmaceutical Assessment of Melia azedarach Gum as a Binder and Disintegrant in Immediate-Release Tablets

Table 1

Master formula for preparation of granules.

Formulation code	Ingredients (mg/tablet)
	Disintegrant	Disintegrant	Binder	Binder	Diluent	Lubricant and glidant
	Melia gum	Starch	Tragacanth	Melia gum	Lactose	Talc
F1	30.0	-	10.0	-	70.0	0.5
F2	60.0	-	10.0	-	40.0	0.5
F3	-	30.0	10.0	-	70.0	0.5
F4	-	60.0	10.0	-	40.0	0.5
F5	-	45.0	25.0	-	55.0	0.8
F6	-	45.0	50.0	-	55.0	0.8
F7	-	45.0	-	25.0	55.0	0.8
F8	-	45.0	-	50.0	55.0	0.8

Each batch contained paracetamol (500 mg) as the active pharmaceutical ingredient (API).