Pharmaceutical Assessment of Melia azedarach Gum as a Binder and Disintegrant in Immediate-Release Tablets

Table 4

Flow properties of formulated granules from Melia gum.

Formulation	Bulk density (g/mL)	Tapped density (g/mL)	Carr’s index (%)	Hausner’s ratio	Angle of repose (θ)
F1	0.471 ± 0.02	0.544 ± 0.01	13.419 ± 0.02	1.155 ± 0.02	23.199 ± 0.02
F2	0.466 ± 0.01	0.596 ± 0.02	21.812 ± 0.01	1.279 ± 0.02	25.821 ± 0.01
F3	0.414 ± 0.02	0.517 ± 0.03	19.923 ± 0.02	1.246 ± 0.01	26.565 ± 0.02
F4	0.409 ± 0.01	0.516 ± 0.02	20.736 ± 0.01	1.262 ± 0.01	26.565 ± 0.01
F5	0.394 ± 0.03	0.466 ± 0.01	15.451 ± 0.02	1.183 ± 0.02	26.565 ± 0.02
F6	0.405 ± 0.02	0.501 ± 0.01	19.162 ± 0.01	1.237 ± 0.01	27.759 ± 0.01
F7	0.413 ± 0.01	0.631 ± 0.02	35.548 ± 0.02	1.528 ± 0.02	33.690 ± 0.03
F8	0.420 ± 0.01	0.588 ± 0.01	28.751 ± 0.03	1.400 ± 0.02	27.759 ± 0.01

The values are mean ± SD, n = 3.