Research Article
Pharmaceutical Assessment of Melia azedarach Gum as a Binder and Disintegrant in Immediate-Release Tablets
Table 5
Physicomechanical properties of the batches of paracetamol tablets produced.
| | Batch No. | Friability (%) | Assay (%)
n = 3 | Average weight (g) n = 20 | Hardness (kg/f)
n = 6 | Disintegration time (min) n = 3 |
| | 1 | 0.1 | 98.70 ± 0.01 | 0.639 ± 0.00 | 4.740 ± 0.08 | 13.55 ± 0.01 | | 2 | 0.1 | 99.50 ± 0.09 | 0.639 ± 0.00 | 4.722 ± 0.03 | 7.55 ± 0.01 | | 3 | 0.1 | 97.21 ± 0.05 | 0.637 ± 0.00 | 4.630 ± 0.03 | 12.12 ± 0.01 | | 4 | 0.2 | 99.20 ± 0.09 | 0.639 ± 0.00 | 4.775 ± 0.06 | 6.12 ± 0.01 | | 5 | 0.1 | 99.81 ± 0.08 | 0.629 ± 0.00 | 4.850 ± 0.06 | 6.20 ± 0.01 | | 6 | 0.1 | 99.61 ± 0.07 | 0.639 ± 0.00 | 5.027 ± 0.08 | 10.36 ± 0.02 | | 7 | 0.1 | 97.81 ± 0.06 | 0.630 ± 0.00 | 4.827 ± 0.05 | 5.46 ± 0.03 | | 8 | 0.1 | 99.42 ± 0.04 | 0.630 ± 0.00 | 4.807 ± 0.06 | 9.34 ± 0.04 |
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