The Scientific World Journal

This work investigates the following generalization of the Fokas–Lenells equation. which is a Schrdinger-type equation with applications in theory of communications. Here, the coefficients are variables and depend on the temporal variable . The improved tanh–coth method is used to obtain exact solutions for it in a general form. If the coefficients turn constants, the equation is known as the standard Fokas–Lenells equation (FLE) which has several applications in nonlinear science. As a particular case, novel soliton solutions, chirped solutions, and the respective chirps associated with them are derived for (FLE). Also, the work explores the behaviour of the solutions when the coefficients change in time, obtaining novel structures of the solutions which help understand in a better way the phenomenon described by the (FLE). We show the graphs of some of the solutions with the aim to compare the two cases, variable and constant coefficients. Finally, some conclusions are given.

The genus Hypericum comprises a large number of species. The flower, leaf, stem, and root of the Hypericum species are widely used in traditional medicine in different cultures. Many Hypericum species have been well investigated phytochemically and pharmacologically. However, only a few reports are available on the H. cordifolium native to Nepal. The present study aims to evaluate the phytochemical composition of different extracts, qualitative analysis of methanol extract of the flower and leaf using thin-layer chromatography (TLC), and the antioxidant properties of components by the TLC-DPPH^. assay. The phenolic and flavonoid contents were estimated in different extracts of the leaf and stem, and their antioxidant and antibacterial activities were evaluated. In the phytochemical screening, phenolics and flavonoids were present in ethyl acetate, methanol, and 50% aq methanol extracts of both the leaf and stem. In TLC analysis, the methanol extract of flowers showed the presence of 11 compounds and the leaf extract showed the presence of 8 compounds. Both extracts contained chlorogenic acid and mangiferin. Hyperoside and quercetin were present only in the flower extract. In the TLC-DPPH^. assay, almost all of the flower extracts and 5 compounds of the leaf extract showed radical scavenging potential. Estimation of phenolics and flavonoids showed that all the leaf extracts showed higher amounts of phenolics and flavonoids than stem extracts. Among leaf extracts, greater amounts of phenolics were detected in 50% aqueous methanol extract (261.25 ± 1.66 GAE/g extract) and greater amounts of flavonoids were detected in methanol extract (232.60 ± 10.52 CE/g extract). Among stem extracts, greater amounts of flavonoids were detected in the methanol extract (155.12 ± 4.30 CE/g extract). In the DPPH radical scavenging assay, the methanol extract of the leaf showed IC₅₀ 60.85 ± 2.67 µg/ml and 50% aq. methanol extract of the leaf showed IC₅₀ 63.09 ± 2.98 µg/ml. The methanol extract of the stem showed IC₅₀ 89.39 ± 3.23 µg/ml, whereas ethyl acetate and 50% aq. methanol extract showed IC₅₀ > 100 µg/ml. In the antibacterial assay, the methanol extract of the leaf showed the inhibition zone of 12-13 mm and the stem extract showed the inhibition zone of 7–11 mm against S. aureus, E. coli, and S. sonnei, whereas both extracts were inactive against S. typhi. The findings of this study support the traditional use of this plant in Nepal for the treatment of diseases associated with bacterial infections. The present study revealed that the underutilized anatomical parts of H. cordifolium could be the source of various bioactive phytochemicals like other Hypericum species.

Irrigation development, particularly small-scale irrigation, is one of the most important projects for improving agricultural productivity in a country’s rural communities. The extent to which small-scale irrigation has improved household livelihoods in Ethiopia’s rural areas is not widely recognized. As a result, research on the influence of small-scale irrigation on farmers’ livelihoods in the Legehida district will be sought. The study took a “with” and “without” strategy, comparing farmers who used irrigation against those who did not. For analysis, both quantitative and qualitative data were employed. The survey’s respondents were chosen using a random sample approach from both irrigation users and nonuser households. Quantitative data for the study were collected from randomly selected 241 farm households, of which 113 were users and 128 were nonusers, using a semistructured questionnaire. Accordingly, the propensity score matching model was employed to examine the impacts of small-scale irrigation on farmers’ livelihoods. The logit model result indicates that cultivated land size, off-farm income, education level, family size, dependency ratio, total livestock unit, and distance to the nearest agricultural extension office/FTC are determinant factors in determining whether to practice irrigation when other factors remain constant. The impact of irrigation on a household’s income and food security (in terms of daily calorie intake) was evaluated using a propensity score matching model. The result shows that a positive and significant impact on farmers who use small-scale irrigation has increased the daily calorie intake and annual income of households by 244.162 kilocalories and 5234.258 ETB, respectively, as compared to nonirrigation users. This shows that households that participate in small-scale irrigation activities have a higher annual income and food security status than comparable groups. In general, the study recommends that to reduce food insecurity and the socioeconomic problems of rural households, irrigation farming is one of the viable solutions; therefore, the government and nongovernmental organizations should extensively focus on the enhancement of small-scale irrigation infrastructure, policies, strategies, and extension services to increase productivity, income, and livelihood improvement in rural households.

Carbon nanotube-FETs (CNTFETs) have become a potential challenger because of their exceptional electrical properties and compatibility with conventional CMOS technology. The design and study of digitally tunable transconductance amplifiers (DTTAs) using CNTFETs are the main topics of this work. By utilizing the special characteristics of CNTFETs, the suggested DTTA design makes transconductance tunable, providing a versatile method of adjusting amplifier settings without requiring modifications to the hardware architecture. This study provides a complete description of the CNTFET modeling techniques utilized for realistic circuit simulations, along with a detailed analysis of the DTTA based on CNTFETs. The circuit is implemented using a 32 nm CNTFET model and verified results with HSPICE.

Background and Aim. Down syndrome (DS) is the most common reason for disabilities caused by genetic disorders. Due to the special nature of this disease and the special needs of children with Down syndrome, they are required to receive their families’ support. Therefore, the recognition of their problems and needs and also the alternatives for resolving them and promoting their life quality are very useful. Also, since very limited qualitative studies have been conducted, it seems necessary to design a qualitative study. Method. This qualitative study was conducted by the content analysis method and through purposeful sampling method with the participation of 26 participants including 15 mothers, 6 fathers, 3 sisters, and 2 brothers of DS children in 2022-2023. The data were collected through semi-structured interviews. Findings. Using the content analysis method of Graneheim and Lundman (2004), the main theme was “Family self-supporting in protecting Down syndrome children.” The subthemes were seven including “trying to find information-support resources,” “Giving importance to child’s health,” “religious beliefs of the family,” “child moral education, helping to child’s relative self-support,” “developing familial support,” and “developing child’s social interactions.” Conclusion and Recommendations. The findings of this study showed that family is the main source of fulfilling the needs of children and their life challenges through using efficient self-support methods. This study introduced family self-support methods in terms of DS children in a way that other families can also manage the problems of their children more efficiently. The present study can be used by trustees of DS to support them and their families. Considering the existence of many problems in children with Down syndrome and the involvement of families, it is suggested that policymakers and community health managers provide the basis for receiving services and social support. For example, it is possible to strengthen the screening systems in the country to diagnose the disease on time and take quick action to solve this problem. Also, by increasing the health insurance coverage and fair distribution of the support resources needed by these people, it promoted the quality of life for them and their families. Also, health policymakers in Iran can take action to increase life expectancy and reduce deaths caused by DS by improving the equitable distribution of health resources and services. Also, public policies should enhance supportive intermediation for prevention and life quality promotion and also decrease health challenges. They are also supposed to lessen the costs of health care. Furthermore, to support social organizations, health service providers and researchers should consider the development of intermediations for the health enhancing and life quality promoting of DS children.

The dried stigmas of Crocus sativus L. produce saffron, a precious spice used for its culinary and medicinal properties since ancient times, while its petals are considered the main by-product of saffron production. The present study aimed to comparatively evaluate the phenolic content, antioxidant capacity, and antibacterial activity of methanolic extracts of stigmas and petals of Crocus sativus L. from Taliouine. The polyphenol content was measured using the Folin–Ciocalteu method, the antioxidant activity was determined using the DPPH free radical scavenging method, and the well-diffusion method was used to assess antibacterial activity against seven pathogenic bacterial strains (Bacillus subtilis, Escherichia coli, Listeria monocytogenes, Proteus vulgaris, Pseudomonas aeruginosa, Salmonella enterica, and Staphylococcus aureus). Furthermore, the minimum inhibitory concentration (MIC) of the extracts was determined using the microdilution broth test. Our findings revealed that stigmas and petals contained phenolic compounds at the rate of 56.11 ± 4.70 and 64.73 ± 3.42 mg GAE/g, as well as DPPH radical scavenging capacity with IC₅₀ of 1700 µg/ml and 430 µg/ml, respectively. Petal extract showed more effective antibacterial activity, with inhibition diameters ranging from 10.66 ± 0.57 to 22.00 ± 1.00 mm and MIC values ranging from 2.81 to 5.62 mg/ml, compared to the stigma extract, which displayed inhibition diameters from 10.00 ± 0.00 to 18.67 ± 0.76 mm and MIC from 2.81 to 11.25 mg/ml, against five of the seven bacterial strains tested, including S. aureus, E. coli, P. vulgaris, P. aeruginosa, and S. enterica. Statistical analyses were performed to determine the significance of these results. Thus, stigmas and petals of Crocus sativus L. might serve as a suitable source of natural antioxidant and antimicrobial agents for application in the food and pharmaceutical industries.