In recent years, a companion diagnosis for prediction of the effectiveness and the side effects after administration of drugs has become very important to decide a therapeutic strategy. In USA, Food and Drug Administration (FDA) recommends the development of the companion diagnostic agent simultaneously with a new drug development. Nuclear Medicine Imaging using positron emission tomography (PET) or single photon emission computed tomography (SPECT), which visualizes target molecules, is able to detect biological and biochemical changes in the earlier phases of diseases differing from an anatomical imaging using X-ray computed tomography (X-ray CT) or magnetic resonance imaging (MRI). Radiolabeled tracers for the nuclear medicine have great potential to provide a lot of information about pathology of individual patients depending on characteristics of each tracer and could be the companion diagnostics. Accordingly, molecular imaging and imaging-based therapy using radiolabeled tracers must contribute to the realization of personalized medicine.

We are interested in research articles as well as review articles about development and usefulness of radiolabeled compounds for molecular imaging and imaging-based therapy. Potential topics include, but are not limited to:

• Radiolabeled compounds for early detection of therapeutic effects
• Hypoxia imaging
• Predicting therapeutic effect of molecular targeted anticancer drugs
• Receptor imaging and evaluation of receptor occupancy
• Bone disorder imaging
• Diagonosis of Alzheimer's disease
• Imaging of atherosclerotic plaques
• Quantification of blood flow and metabolism
• Imaging of inflammatory disorders

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