Lycopene Prevents Development of Steatohepatitis in Experimental Nonalcoholic Steatohepatitis Model Induced by High-Fat Diet

Table 3

The effects of lycopene supplementation on MDA and glutathione levels in groups.

Parameter	Control group ($n=10$)	HFD ($n=10$)	HFD $+$ 2 mg/kg lycopene ($n=9$)	HFD $+$ 4 mg/kg lycopene ($n=10$)
Plasma MDA (nmol/mL)	$\mathrm{2,06}\pm 0.54$	$\mathrm{4,28}\pm 0.94$^†	$\mathrm{2,58}\pm \mathrm{0,54}$ *	$\mathrm{2,12}\pm \mathrm{0,51}$ *
Liver MDA (nmol/gr)	$\mathrm{20,72}\pm 2.70$	$\mathrm{29,8}\pm \mathrm{3,91}$^†	$\mathrm{20,21}\pm \mathrm{4,39}$ *	$\mathrm{15,89}\pm \mathrm{4,65}$ *
Liver glutathione ($\mu$mol/mg)	$\mathrm{9,07}\pm \mathrm{1,01}$	$\mathrm{8,08}\pm \mathrm{1,19}$	$\mathrm{22,62}\pm \mathrm{20,09}$ *	$\mathrm{20,96}\pm \mathrm{3,91}$ *

* $P<.001$: compared with high-fat diet group; ^†$P<.001$: versus control group.