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Veterinary Medicine International
Volume 2011, Article ID 180206, 5 pages
http://dx.doi.org/10.4061/2011/180206
Review Article

Oxidative Stress in Dog with Heart Failure: The Role of Dietary Fatty Acids and Antioxidants

1ENVT, 2 allée des Cèdres 66330 Cabestany, France
2ENVT, INRA, UMR 1089, Université de Toulouse, 31076 Toulouse, France

Received 30 December 2010; Accepted 14 February 2011

Academic Editor: Cristina Castillo Rodríguez

Copyright © 2011 Emmanuelle Sagols and Nathalie Priymenko. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

In dogs with heart failure, cell oxygenation and cellular metabolism do not work properly, leading to the production of a large amount of free radicals. In the organism, these free radicals are responsible of major cellular damages: this is oxidative stress. However, a suitable food intake plays an important role in limiting this phenomenon: on the one hand, the presence of essential fatty acids in the composition of membranes decreases sensitivity of cells to free radicals and constitutes a first protection against the oxidative stress; on the other hand, coenzyme Q10, vitamin E, and polyphenols are antioxidant molecules which can help cells to neutralize these free radicals.