Research Article

Effect of Therapy by Using Advocate Spot-On Combination (Imidacloprid 10% and Moxidectin 2.5%) on Subcutaneous Dirofilariosis in Dogs

Table 1

The influence of Advocate on the presence of Dirofilaria repens microfilariae in the blood of tested dogs.

ExaminationTreatment††
Number of microfilariae/mL blood

11752926513528301872950215580725246
2
113

106

168

1838

2169

119

2105

184

412

633

730
3
0

0

0

0

0

0

0

0

0

0

0
4
0

0

0

0

0

0

0

0

0

0

0
5
0

0

0

0

0

0

0

0

0

0

0
6
0

0

0

0

0

0

0

0

0

0

0
7
0

0

0

0

0

0

0

0

0

0

0
8
0

0

0

0

0

0

0

0

0

0

0
9
0

0

0

0

0

0

0

0

0

0

0
10
0

0

0

0

0

0

0

0

0

0

0
11
0
Dog 1

0
Dog 2

0
Dog 3

0
Dog 4

0
Dog 5

0
Dog 6

0
Dog 7

0
Dog 8

0
Dog 9

0
Dog 10

0
Dog 11

Examinations were performed monthly (in one month interval).
††Treatment with Advocate, Bayer (imidacloprid at 10–25 mg/kg and moxidection at 2.5–6,5 mg/kg) monthly for four months (— no treatment, treatment).