Effect of Therapy by Using Advocate Spot-On Combination (Imidacloprid 10% and Moxidectin 2.5%) on Subcutaneous Dirofilariosis in Dogs
Table 1
The influence of Advocate on the presence of Dirofilaria repens microfilariae in the blood of tested dogs.
Examination†
Treatment††
Number of microfilariae/mL blood
—
—
—
—
—
—
—
—
—
—
—
1
175
29
265
135
2830
187
2950
215
580
725
246
2
√ 113
√ 106
√ 168
√ 1838
√ 2169
√ 119
√ 2105
√ 184
√ 412
√ 633
√ 730
3
√ 0
√ 0
√ 0
√ 0
√ 0
√ 0
√ 0
√ 0
√ 0
√ 0
√ 0
4
√ 0
√ 0
√ 0
√ 0
√ 0
√ 0
√ 0
√ 0
√ 0
√ 0
√ 0
5
√ 0
√ 0
√ 0
√ 0
√ 0
√ 0
√ 0
√ 0
√ 0
√ 0
√ 0
6
— 0
— 0
— 0
— 0
— 0
— 0
— 0
— 0
— 0
— 0
— 0
7
— 0
— 0
— 0
— 0
— 0
— 0
— 0
— 0
— 0
— 0
— 0
8
— 0
— 0
— 0
— 0
— 0
— 0
— 0
— 0
— 0
— 0
— 0
9
— 0
— 0
— 0
— 0
— 0
— 0
— 0
— 0
— 0
— 0
— 0
10
— 0
— 0
— 0
— 0
— 0
— 0
— 0
— 0
— 0
— 0
— 0
11
— 0 Dog 1
— 0 Dog 2
— 0 Dog 3
— 0 Dog 4
— 0 Dog 5
— 0 Dog 6
— 0 Dog 7
— 0 Dog 8
— 0 Dog 9
— 0 Dog 10
— 0 Dog 11
†Examinations were performed monthly (in one month interval). ††Treatment with Advocate, Bayer (imidacloprid at 10–25 mg/kg and moxidection at 2.5–6,5 mg/kg) monthly for four months (— no treatment, √ treatment).